Protein Alignment mam and maml3

DIOPT Version :9

• Sequence 1: NP_001286401.1
• Gene: mam / 36555
• FlyBaseID: FBgn0002643
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_005160069.1
• Gene: maml3 / 101886283
• ZFINID: ZDB-GENE-090313-292
• Length: 1099
• Species: Danio rerio
• Alignment Length: 1540
• Identity: 349/1540 - (22%)
• Similarity: 463/1540 - (30%)
• Gaps: 622/1540 - (40%)

  Fly    85 HSPYNANLGATGGIAGITGGNGAGGPTNPGAVPTAPGDTMPTKRMPVVDRLRRRMENYRRRQTDC 149
            :|..|.|.......:|.|||         |.:|         |...||:|||:|:|..||...:|
Zfish    21 NSNVNLNSAINAANSGSTGG---------GNIP---------KHSTVVERLRQRIEGCRRHHVNC 67

  Fly   150 VPRYEQAFNTVCEQQNQETTVLQKRFLESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQ 214
            ..||:||.....|...:||..|.:|.||.:    |||::         :.:||.:||:.......
Zfish    68 ESRYQQAHAEQLELDRRETVSLYQRSLEQR----AKKSN---------NSKQQSKQQEPDSSASA 119

  Fly   215 HQQAQTMLAGQLQSSVHVQQKFLKRPAEDVDNGPDSFEPPHKLPNNNNNSNSNNNNGNANANNGG 279
            .|:..|::|.|                |.|....||...|              .||:.|..:.|
Zfish   120 EQRNSTLIALQ----------------ETVKRKLDSARSP--------------LNGDQNGLSDG 154

  Fly   280 NGSNTGNNTNNNGNSTNNNGGSNNNGSENLTKFSVEIVQQLEFTTSAANSQPQQISTNVTVKALT 344
            :.|.|.......|.:          |.::|                  .|.|       .:..|.
Zfish   155 SYSPTTKRLRKEGCT----------GMDSL------------------GSLP-------PISPLH 184

  Fly   345 NTSVKSEPGVGGGGGGGGGGGSGNNNNNGGGGGGGNGNNNNNGGDHHQQQHQQQQQQQGGGLGGL 409
            ...:|  |.:          .||||:     ....||..|.|.|.:|.....:.          |
Zfish   185 QMDIK--PTL----------PSGNNS-----ASSNNGTGNGNAGTNHITGRPED----------L 222

  Fly   410 GNNGRGGGPGGMATGPGGVAGGLGGMGMPPNMMSAQQKSALGNL------ANLVECKREPDHDFP 468
            |.||                      |||...::       |:|      :.|.:.|:||
Zfish   223 GKNG----------------------GMPDIKLN-------GSLDLDDGFSLLKDLKQEP----- 253

  Fly   469 DLGSLDKDGGG---------GQFPGFPDLLGDDNSENNDTFKDLINNL------QDFNPSFLDGF 518
                || ||.|         .|...|.|:     :.|:..:::||:.|      .|.:..|.:.|
Zfish   254 ----LD-DGAGIESSETSLSNQNKLFSDI-----NLNDQEWQELIDELANTVPEDDMHDLFNEDF 308

  Fly   519 DEKPLL--------------------DIKTEDGIKVEPPNAQDLINSLNVKSEGGLGHGFGGFGL 563
            :||..:                    .:.|......:|.:.|..:.|..|:.... |..|.....
Zfish   309 EEKKEVSDFTRVTTEQTQLAQDPAPNSVATAPNSAPQPQSGQMPMGSPQVRPSSS-GPPFATAAS 372

  Fly   564 GL-------DNPGMKMRGGNPGN--------------QGGFPN-----------GPNGGT---GG 593
            |.       .:|.:.|..|:|.|              |...|.           ||.|.|   ||
Zfish   373 GTPPQQPLQQSPAVGMPSGSPANCVARSPQTPTQAQTQASRPGNGFMMNAGPAVGPVGSTPVAGG 437

  Fly   594 APNAGGNGGNSGNLMSEHPLAAQTLKQMAEQHQHKNAMGGMGGFPRPPHG-MNPQQQQQQQQQQQ 657
            .|.:||.||                                ||.|.||.. ::|.:|.:|...||
Zfish   438 GPGSGGTGG--------------------------------GGVPVPPTSELSPAEQLKQMAAQQ 470

  Fly   658 QQQA---QQQHGQMMGQGQPGRY-------NDYGGGFPNDFGLGPNGPQQQQQAQQQQPQQQHLP 712
            ||:|   ||:|.|   |.|...:       :.|.|.|..|   .||.|....||
Zfish   471 QQRAKLIQQKHQQ---QSQAANWSPAGAPTSPYSGPFNPD---KPNSPMMYTQA----------- 518

  Fly   713 PQFHQQKGPGPGAGMNVQQNFLDIKQELFYSSQNDFDLKRLQQQQAMQQQQQQQHHQQQQQQQQP 777
              |:.....||.|
Zfish   519 --FNPSNTMGPKA---------------------------------------------------- 529

  Fly   778 KMGGVPNFNKQQQQQQVPQQQLQQQQQQQQQQQ------QQQQQQYSPFSNQNP---NAAANFLN 833
                 |:.|     ..:||..:....|||||||      |....:...|||..|   .:..:.:|
Zfish   530 -----PSIN-----NYLPQNHINMLNQQQQQQQPNNLAAQNSHNKQLSFSNTKPLTHFSGVDHMN 584

  Fly   834 ---CPPRGGPNGNQQPGNLAQQQQQPGAGPQQQQQRGNAANGQQNNPNAGPGGNTPNAPQQQQQQ 895
               .||            :|.|.:    .|.....:||||.          ||..|.||.....|
Zfish   585 QRMTPP------------MANQAK----NPMMPYMQGNAAQ----------GGGPPQAPGPMPSQ 623

  Fly   896 STTTTLQMKQTQQLHISQQGGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQ 960
              |..|..:|.:.:.:.|:                    |.|       ||:.:...|...|:..
Zfish   624 --TAHLSEEQKKMMILKQK--------------------MMS-------QGLPYGPMQPHVQEVV 659

  Fly   961 QQPGGTNGPNPQQQQQQPHGGNAGGGVGVGVGVGVGNGG--PNPGQQQQQPNQNMSNANVPSDGF 1023
            ..|....|..|      ||||  .|||......|.|.||  |||.||||........|.......
Zfish   660 GLPRQAGGVQP------PHGG--PGGVAPAGPNGAGPGGYLPNPQQQQQAAMMKQMMAMEQEKRV 716

  Fly  1024 SL---SQSQSMNF-----NQQQQQQAAAQQQQVQPNMRQRQTQAQA---AAAAAAAAAQAQAAAN 1077
            .|   .|.|....     .|||||...|:|.|.|.::.::.||||.   ........:|..||.|
Zfish   717 QLHLMEQQQKAQLMREQRQQQQQQHMLAEQLQQQQHLPRQMTQAQRNPYPLQQFQGTSQEMAARN 781

  Fly  1078 ASGPNV---PLMQQPQVGVGVGVGVGVGVGVGNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQM 1139
            .:..|:   .||||.|                                   |..      |||
Zfish   782 QTLQNMRTARLMQQQQ-----------------------------------QQN------PGM-- 803

  Fly  1140 GGPMNPMQMNP--NAAG-PTAQQMMMGSGAGGPGQVPGPGQGPNPNQAKFLQQQQMMRAQAMQQQ 1201
                  |||.|  |||. ||...|.|..| |..|...|..||.|||..:.||          |||
Zfish   804 ------MQMTPVQNAAAMPTQGDMSMAYG-GQAGAQTGMYQGMNPNMGQMLQ----------QQQ 851

  Fly  1202 QQHMSGARPPPPEYNATKAQLMQAQMMQQTVGGGGVGVGGVGVGVGVGGVGGANGGRFPNSAAQA 1266
            |.|.:.|               ...|.|:..|.||.|:.|.|.|.|.|.....|    ||.:.|
Zfish   852 QHHPNQA---------------SMAMAQRQAGAGGQGMVGGGAGAGYGQAMLMN----PNLSQQ- 896

  Fly  1267 AAMRRMTQQPIPPSGPMMRPQHAMYMQQHGGAGGGPRTGMGVPYGGGAGGPMGGPQQQQ------ 1325
                ::....:.|.|..|.......:|...|.||                 ...|||||
Zfish   897 ----QLKSAGVAPGGQPMAKAQVQRLQSMMGGGG-----------------QAWPQQQQNMQAMA 940

  Fly  1326 -RPPNVQVTPDGMPMGSQQEWRHMMMTQQQTQMGFGGPGPGGPMRQGPGGFNGGNFMPN------ 1383
             |..|..|..:..|..:.|..:...|.:|......||.....|....|... ||..||:
Zfish   941 GRTSNDMVAFNSNPAYAMQGGQPPRMAKQHFAQAMGGQTMVDPRSINPAAM-GGPMMPHMAGQPR 1004

  Fly  1384 --------------GAPNGAA-GSGPNAGGMM-----SGPNVPQMQLTPAQMQQQLMRQQQQQQQ 1428
                          |.||.|| |.|| |.||.     .||.:|..|           .|..|:..
Zfish  1005 TNQPRGMVMPGMNQGVPNMAAFGQGP-AQGMPGASGGGGPYMPGGQ-----------PQGYQRTS 1057

  Fly  1429 QQQQHMGPGAANNMQMQQLLQQQQSGGGGNMMASQMQMTSMHMTQ 1473
            .|:...|.|:             |||.|..:.......|.:..|:
Zfish  1058 NQELAYGYGS-------------QSGAGAGVSFGLSDGTDLDSTE 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mam	NP_001286401.1	MamL-1	127..183	CDD:286652	22/55 (40%)
maml3	XP_005160069.1	MamL-1	44..101	CDD:286652	25/69 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4577
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050