Protein Alignment mam and maml2

DIOPT Version :9

• Sequence 1: NP_001286401.1
• Gene: mam / 36555
• FlyBaseID: FBgn0002643
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_031753184.1
• Gene: maml2 / 100493991
• XenbaseID: XB-GENE-987036
• Length: 994
• Species: Xenopus tropicalis
• Alignment Length: 1291
• Identity: 267/1291 - (20%)
• Similarity: 385/1291 - (29%)
• Gaps: 477/1291 - (36%)

  Fly    89 NANLGATGGIAGITGGNGAGGPTNPGAVPTAPGDTMPTKRMPVVDRLRRRMENYRRRQTDCVPRY 153
            |..:|..|  ||:.||                |...|.....:|:|||.|:...|:...:|..||
 Frog    13 NLGIGVAG--AGLLGG----------------GSVTPRIHSAIVERLRARIAVCRQHHLNCEGRY 59

  Fly   154 EQAFNTVCEQQNQET----TVLQKRFLESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQ 214
            |::.....:::.:.|    |::|......||.:..|.|  ..|.|...|..|||.|..:.::...
 Frog    60 ERSRAESSDRERENTLHLLTLVQHGQGTRKNNKHNKST--CAPPPDYHHHHQQHLQSTEGKEING 122

  Fly   215 HQQAQTMLA-GQLQSSVHVQQKFLKR----PAEDV-DNG--PDSFEPPHKLPNNN---NNSNSNN 268
            :||.|:... .|..|::...|..|||    ||:.. .||  ..||....||.|.:   ..|..:|
 Frog   123 NQQPQSSNGLNQRNSALIALQGSLKRRIVPPAQSKRPNGISDHSFLDFKKLKNEHLLAAQSRYHN 187

  Fly   269 NNGNANANNGGN-----GSNTGNNTNNNGNSTNNNGGSNNNGSENLTKFSVEIVQQLEFTTSAAN 328
            .:|...|::|..     |..:.:|||||.|...|          :|..|:::
 Frog   188 VDGMKLASSGDRQMELAGPRSTDNTNNNSNCNVN----------DLFSFALK------------- 229

  Fly   329 SQPQQISTNVTVKALTNTSVKSEPGVGGGGGGGGGGGSGNNNNNGGGGGGGNGNNNNNGGDH--- 390
                              .:|.|||                             ...:.|.|
 Frog   230 ------------------DIKKEPG-----------------------------EAVSCGKHLDV 247

  Fly   391 ---HQQQHQQQ----QQQQGGGLGGLGNNGRGGGPGGMATGPGGVAGGLGGMGMPPNMMSAQQKS 448
               |:.|.:.:    :|.....|..|.|.                   |..:.:||     ...:
 Frog   248 PLSHENQLKYEEDSGEQFMDPDLQELFNE-------------------LTYISVPP-----MSDT 288

  Fly   449 ALGNLANLVECKREPDHDFPDLGSLDKDGGGGQFPGFPDLLGDDNSENNDTFKDLINNLQDFNPS 513
            .|.|:.|:...:.||.|  .|:|..::.......|
 Frog   289 ELQNMINITIKQDEPFH--IDIGHQNQRTTSSSMP------------------------------ 321

  Fly   514 FLDGFDEKPLLDIKTEDGIKVEPPNAQDLINSLNVKSEGGLGHGFGGFGLGLDNPGMKMRGGNPG 578
                                         ::.:.:|||         :..|||...:......|.
 Frog   322 -----------------------------LDKVTIKSE---------YSPGLDPARVASPQLRPS 348

  Fly   579 NQG-GFPNGPNGGTGGAPNAGGNGGNSGNLMSEHPLAAQTLKQMAEQHQHKNAMGGMGGFPRPPH 642
            :.| .||                       ||..||.:.           .||..        ||
 Frog   349 STGPAFP-----------------------MSSAPLTST-----------PNATA--------PH 371

  Fly   643 GMNPQQ------------QQQQQQQQQQQQAQQQHGQMMGQGQPGRYNDYGGGFPNDFGLGPN-- 693
              ||.|            |:....||.:|.|..:...::.|.||.:.:.:....|.  ||.|.
 Frog   372 --NPSQTQVSGTNRLHSWQELSHAQQLKQIAANRQNNIIHQHQPSQPSSWPTMSPT--GLSPRPF 432

  Fly   694 ------GPQQQQQAQQQQPQQQHLPPQFHQQKGPGPGAGMNVQQNFLDIKQELFYSSQNDFDLKR 752
                  .|.:.||.....|....:|..         ||...:..::| .||..  ||||:.: :.
 Frog   433 GDVKVPSPFRHQQLSPHSPSTSAVPVN---------GAQSKMMSSYL-YKQNA--SSQNNSN-EL 484

  Fly   753 LQQQQAMQ-----QQQQQQH-------HQQQQQQQQPKMGGVPNFNK-----QQQQQQVPQQQLQ 800
            ::.|.|.:     ..|:|.|       |..|.|..|.....|.|.||     .||:||.|..  :
 Frog   485 IKAQDAAKCAVTNSTQEQIHSNIKPLFHFNQDQPNQQISSAVSNPNKPVLQFPQQKQQTPTS--K 547

  Fly   801 QQQQQQQQQQQQQQQQYSPFSNQNPNAAANFLNCP--PRGGPNGNQQPGNLAQQQQQPGAGPQQQ 863
            |..:|.||.|....||.|     .|......:..|  |:..|.......::..||.|..|.....
 Frog   548 QHHEQTQQVQSVSNQQLS-----RPTTFQQKMTFPKLPQNQPISGLHYSSVHSQQDQHSATAPGT 607

  Fly   864 QQRGNAANGQQNNPNAGPGGNTPNAPQQQQQQSTTTTLQ---MKQTQQLHISQQGGGAHGIQVSA 925
            ....|.|:..  :||.|.|.::......||.......||   |:|.|||.:.||
 Frog   608 PTSSNPASCA--SPNTGNGYSSQQPLSAQQLMEKANALQRQMMEQKQQLLLQQQ----------- 659

  Fly   926 GQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQQQPGGTNGPNPQQQQ--------QQPHGGN 982
                .|:|..|||                    .|.|....|.|.|..:.        |||....
 Frog   660 ----MLAGMEKSN--------------------SQDQMSHLNRPPPDYKDQRRSSVGLQQPASHY 700

  Fly   983 AGGGVGVGVGVGVGNGGPNPGQQQQQPNQNMSNANVPSDGFSLSQSQSMNFNQQQQQQAAAQQQQ 1047
            :.|...|||     |..| |......|..|::..| ||       ..|.|.:.:......||...
 Frog   701 SNGLPTVGV-----NQSP-PATTNPVPTHNLTPPN-PS-------HSSPNHSSRMTPLPGAQNMY 751

  Fly  1048 VQPNMRQRQTQAQAAAAAAAAAAQAQAAANASGPN-----VPLMQQPQVGVGVGVGVGVGVGVGN 1107
            ......|   ||...|:..|:..|.|.:.|..|.|     :| .|.|.
 Frog   752 GTAPCSQ---QAMYNASPGASKMQQQTSPNTLGSNQNSHILP-RQSPS----------------- 795

  Fly  1108 GGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQMGGPMNPMQMNPNAAGPTAQQMMMGSGAGGPGQV 1172
                   |.|.|              :|....|...:|.|..|:          :..|....||.
 Frog   796 -------GQGNP--------------LPPFSAGSATSPPQFRPS----------LNHGTNMAGQR 829

  Fly  1173 PGPGQGPNPNQAKFLQQQQMMRA--------QAMQQQQQHMSGAR---PPPPEYNATKAQLMQAQ 1226
            |..|...:|....:..|:...::        |...|..|.|.|::   |..||..      |:||
 Frog   830 PSNGLINSPVPQIWASQEAKKQSGLCFSNTNQFSNQSLQGMLGSQNFAPNQPELQ------MRAQ 888

  Fly  1227 MMQQTVGGGGVGVGGVGVGVGVGGVGGANGGRF---------PNSAAQAAAMRRMT 1273
            |.|..            .|..:..:.|.|.|:.         ||....:.||...|
 Frog   889 MSQSP------------AGQTMEPLRGFNSGQAQLRAQLSPNPNQGGASTAMAANT 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mam	NP_001286401.1	MamL-1	127..183	CDD:286652	15/59 (25%)
maml2	XP_031753184.1	MamL-1	34..89	CDD:401509	13/54 (24%)
		PHA03247	<309..626	CDD:223021	89/452 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000