DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8067 and PRMT9

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_612373.2	Gene:	PRMT9 / 90826	HGNCID:	25099	Length:	845	Species:	Homo sapiens

Alignment Length:	289	Identity:	58/289 - (20%)
Similarity:	99/289 - (34%)	Gaps:	81/289 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KLTKLSTLKVKCELRALSSLTQTSQHIFDRNAKRLQKERAAL---------------SEDVGLYD 53
            ::..:|.|.::||:....|.||....:...|...|....|.|               |.::.|.:
Human   465 RIQSISVLGLECEMDVAKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLN 529

  Fly    54 YLKEEIGFRLA-DRVFD--IKREFKAAADIGC----SRGYLSRHILAESVEQLTLTDTSA--TML 109
            .:....||::| .:|..  ...:.....|..|    |.|....:.:...:|...:.|.|.  ::|
Human   530 NIPYHEGFKMAMSKVLSSLTPEKLYQTMDTHCQNEMSSGTGQSNTVQNILEPFYVLDVSEGFSVL 594

  Fly   110 EQAQGTPGLKMVK----LVKDEEQLDFEDNSLDLVISSLSLHWVNDLPGCFVRIKQSLK------ 164
            ....||.|  .||    :.||:.::     :|||:..:      |..|      |::|:
Human   595 PVIAGTLG--QVKPYSSVEKDQHRI-----ALDLISEA------NHFP------KETLEFWLRHV 640

  Fly   165 PDGVFIASMFGGDTLYEL-------RSSLQLAELERKGGISPHISPFTQIRDIGSLLNRAGFTML 222
            .|...:......|.|:.:       .|.|...|:..|..||            ..||...|
Human   641 EDESAMLQRPKSDKLWSIIILDVIEPSGLIQQEIMEKAAIS------------RCLLQSGG---- 689

  Fly   223 TIDTDELVIGYPSMFELMWDLKGMAENNA 251
                 ::...|..||.|:.:.:.:.|.||
Human   690 -----KIFPQYVLMFGLLVESQTLLEENA 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	45/220 (20%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	23/106 (22%)
PRMT9	NP_612373.2	TPR 1	25..58
		TPR	<39..144	CDD:223533
		TPR 2	67..100
		TPR repeat	68..95	CDD:276809
		TPR repeat	100..130	CDD:276809
		TPR 3	101..134
		AdoMet_MTases	148..>303	CDD:327401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900