DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8067 and ndufaf5

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001076363.1	Gene:	ndufaf5 / 794020	ZFINID:	ZDB-GENE-070410-110	Length:	321	Species:	Danio rerio

Alignment Length:	313	Identity:	164/313 - (52%)
Similarity:	223/313 - (71%)	Gaps:	10/313 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RALSSLTQTSQHIFDRNAKRLQKERAALSEDVGLYDYLKEEIGFRLADRVFDIKREFKAAADIGC 82
            |:.||  :...::|||:.||.||:.|:...|...||||:||:|.|:||||:|:.|.|..|.|:||
Zfish    16 RSFSS--RQGMNVFDRSMKRRQKDWASSLLDSSKYDYLREEVGSRVADRVYDVARTFPLALDVGC 78

  Fly    83 SRGYLSRHILAESVEQLTLTDTSATMLEQAQGTPGLKMVKLVKDEEQLDFEDNSLDLVISSLSLH 147
            .|.:::.|:..|.||:|.|||.|::.|...: |..:....::.|||.|.|::|:.|||:||||:|
Zfish    79 GRSHIAEHLSKEVVERLFLTDISSSSLRNRK-TSDIPAQCVMADEEFLPFKENTFDLVLSSLSMH 142

  Fly   148 WVNDLPGCFVRIKQSLKPDGVFIASMFGGDTLYELRSSLQLAELERKGGISPHISPFTQIRDIGS 212
            |:|||||...:|.|.||||||||.:|.||:||||||.|||||||||:||.:|||||:|.:.|:|:
Zfish   143 WINDLPGALRQIHQVLKPDGVFIGAMVGGETLYELRCSLQLAELEREGGFAPHISPYTAVTDLGN 207

  Fly   213 LLNRAGFTMLTIDTDELVIGYPSMFELMWDLKGMAENNAAFNRPAHLSRETMLAASAIYQELYAK 277
            ||.:|||.|||:|.||:.:.||.|.|:|.||:||.|:|.|:||...|.|:|||||:|||:|:|.
Zfish   208 LLGQAGFNMLTVDIDEVQVNYPGMLEVMRDLQGMGESNCAWNRKLLLQRDTMLAAAAIYKEMYG- 271

  Fly   278 PNEKG-IPATFQIIYFVGWKPGPNQPQPLERGTGEVSLKDLGSIIEKGGKLDT 329
             ||.| :||||||:|.:||||..:|.:|.:||:..||..||..|    |||.:
Zfish   272 -NEDGSVPATFQILYMIGWKPHDSQAKPAKRGSANVSFADLSKI----GKLQS 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	132/238 (55%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	43/90 (48%)
ndufaf5	NP_001076363.1	BioC	67..290	CDD:273953	124/225 (55%)
ndufaf5	NP_001076363.1	Methyltransf_11	74..165	CDD:285453	43/91 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576776
Domainoid	1	1.000	183	1.000	Domainoid score	I3383
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11474
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2501
OMA	1	1.010	-	-		QHG55980
OrthoDB	1	1.010	-	-		D360753at33208
OrthoFinder	1	1.000	-	-		FOG0004942
OrthoInspector	1	1.000	-	-		oto40032
orthoMCL	1	0.900	-	-		OOG6_102393
Panther	1	1.100	-	-	LDO	PTHR13090
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4328
SonicParanoid	1	1.000	-	-		X4031
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800