DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8067 and NDUFAF5

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_077025.2	Gene:	NDUFAF5 / 79133	HGNCID:	15899	Length:	345	Species:	Homo sapiens

Alignment Length:	300	Identity:	162/300 - (54%)
Similarity:	213/300 - (71%)	Gaps:	4/300 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SLTQTSQHIFDRNAKRLQKERAALSEDVGLYDYLKEEIGFRLADRVFDIKREFKAAADIGCSRGY 86
            |.:..:.:||||:.||.||..||...:...:||||||:|.|:||||:||.|.|..|.|:||.|||
Human    38 STSPRTLNIFDRDLKRKQKNWAARQPEPTKFDYLKEEVGSRIADRVYDIPRNFPLALDLGCGRGY 102

  Fly    87 LSRHILAESVEQLTLTDTSATMLEQAQGTPGLKMVKLVKDEEQLDFEDNSLDLVISSLSLHWVND 151
            :::::..|::.:....|.:...|:.:..|. :..|.::.|||.|.|::|:.|||:||||||||||
Human   103 IAQYLNKETIGKFFQADIAENALKNSSETE-IPTVSVLADEEFLPFKENTFDLVVSSLSLHWVND 166

  Fly   152 LPGCFVRIKQSLKPDGVFIASMFGGDTLYELRSSLQLAELERKGGISPHISPFTQIRDIGSLLNR 216
            ||....:|...||||||||.:|||||||||||.||||||.||:||.||||||||.:.|:|.||.|
Human   167 LPRALEQIHYILKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHISPFTAVNDLGHLLGR 231

  Fly   217 AGFTMLTIDTDELVIGYPSMFELMWDLKGMAENNAAFNRPAHLSRETMLAASAIYQELYAKPNEK 281
            |||..||:||||:.:.||.|||||.||:||.|:|.|:||.|.|.|:|||||:|:|:|:|.  ||.
Human   232 AGFNTLTVDTDEIQVNYPGMFELMEDLQGMGESNCAWNRKALLHRDTMLAAAAVYREMYR--NED 294

  Fly   282 G-IPATFQIIYFVGWKPGPNQPQPLERGTGEVSLKDLGSI 320
            | :|||:||.|.:|||...:|.:|.|||:..||..:||.|
Human   295 GSVPATYQIYYMIGWKYHESQARPAERGSATVSFGELGKI 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	134/238 (56%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	39/90 (43%)
NDUFAF5	NP_077025.2	BioC	74..310	CDD:273953	134/238 (56%)
NDUFAF5	NP_077025.2	Methyltransf_11	94..185	CDD:285453	39/91 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143846
Domainoid	1	1.000	188	1.000	Domainoid score	I3331
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11474
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2539
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55980
OrthoDB	1	1.010	-	-		D360753at33208
OrthoFinder	1	1.000	-	-		FOG0004942
OrthoInspector	1	1.000	-	-		oto90961
orthoMCL	1	0.900	-	-		OOG6_102393
Panther	1	1.100	-	-	LDO	PTHR13090
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4328
SonicParanoid	1	1.000	-	-		X4031
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800