DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8067 and Bud23

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_030110611.1	Gene:	Bud23 / 66138	MGIID:	1913388	Length:	300	Species:	Mus musculus

Alignment Length:	268	Identity:	54/268 - (20%)
Similarity:	85/268 - (31%)	Gaps:	115/268 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KCELRALSSLTQTSQH------IFDRNAKRLQKERAALSEDVGLYDYLKEEIGFRLADRVFDIKR 72
            :|....::|.::..:|      .:|:|..|               .|::.       .|:.||:.
Mouse    14 RCHTIEMASRSRRPEHSGPPELFYDQNEAR---------------KYVRN-------SRMIDIQT 56

  Fly    73 EFKAAA---------------DIGCSRGYLSRHILAESVEQLTLTDTSATMLEQA---------- 112
            :....|               ||||..| ||...::|........|.|..||:.|
Mouse    57 KMTERALELLCLPEGQPSYLLDIGCGSG-LSGDYISEEGHYWVGIDISPAMLDAALDRDTEGDLL 120

  Fly   113 -----QGTPGLKMVKLVKDEEQLDFEDNSLDLVISSLSLHWV------NDLPG----CFVRIKQS 162
                 ||.|               |...|.|..||..::.|:      :|:|.    ||.
Mouse   121 LGDMGQGVP---------------FRPGSFDGCISISAVQWLCNANKKSDVPARRLYCFF----- 165

  Fly   163 LKPDGVFIASMFGGDTLYELRSSLQLAELERKGGISPHISPFTQIRDIGSLLNRAGFTMLTIDTD 227
               ..::.|.:.|.      |:.|||         .|..|  .|:..|.:...||||      |.
Mouse   166 ---SSLYSALVRGA------RAVLQL---------YPENS--EQLELITTQATRAGF------TG 204

  Fly   228 ELVIGYPS 235
            .:|:.:|:
Mouse   205 GVVVDFPN 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	47/218 (22%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	26/115 (23%)
Bud23	XP_030110611.1	UbiG	37..>110	CDD:225137	20/95 (21%)
		Methyltransf_11	77..>147	CDD:369777	21/85 (25%)
		WBS_methylT	223..298	CDD:372208
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810