DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8067 and K09E4.3

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001370103.1	Gene:	K09E4.3 / 175064	WormBaseID:	WBGene00010721	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	296	Identity:	137/296 - (46%)
Similarity:	195/296 - (65%)	Gaps:	5/296 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 IFDRNAKRLQKERAALSEDVGLYDYLKEEIGFRLADRVFDIKREFKAAADIGCSRGYLSRHILAE 94
            :|||..||.|::.|....|.....|||||||:|:||:|||:.:......||||..|:::.|::.|
Worm     2 VFDRQMKRGQRDWAVRQPDFKAAQYLKEEIGWRVADKVFDLTKFNPLVLDIGCGVGHIAPHLIKE 66

  Fly    95 SVEQLTLTDTSATMLEQAQ--GTPGLKMVKLVKDEEQLD-FEDNSLDLVISSLSLHWVNDLPGCF 156
            :|.::...|.|..|.:.:.  ..|.:.:.:...|||.|| |.:|..||:::|:|.||:|.||...
Worm    67 NVGKIIQVDMSGGMAQSSAKCEDPEVIVERRTVDEETLDGFHENQFDLLLTSMSAHWINHLPQWM 131

  Fly   157 VRIKQSLKPDGVFIASMFGGDTLYELRSSLQLAELERKGGISPHISPFTQIRDIGSLLNRAGFTM 221
            .:....:|||..||.||...|||||||.|||||||||.||:|.|||||.:.:|||.||:.|||.|
Worm   132 RKCHDIVKPDCPFIGSMLAEDTLYELRCSLQLAELERIGGVSSHISPFVKTQDIGGLLSSAGFDM 196

  Fly   222 LTIDTDELVIGYPSMFELMWDLKGMAENNAAFNRPAHLSRETMLAASAIYQELYAKPNEKGIPAT 286
            :|:|:||:.:|||:||.||:||:.|.|::....|...:.|:.::||.||||.:|:...:  .|||
Worm   197 ITLDSDEIQVGYPNMFALMYDLQLMGESHCTHRRNPTIRRDVLVAAEAIYQSMYSSDGK--YPAT 259

  Fly   287 FQIIYFVGWKPGPNQPQPLERGTGEVSLKDLGSIIE 322
            |:|:.|:|||||||.|:..:||:..|||||:|.|:|
Worm   260 FKIVSFIGWKPGPNMPKAAKRGSQTVSLKDIGKIVE 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	108/240 (45%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	31/93 (33%)
K09E4.3	NP_001370103.1	Methyltransf_25	49..141	CDD:404528	29/91 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157888
Domainoid	1	1.000	174	1.000	Domainoid score	I2200
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11474
Inparanoid	1	1.050	269	1.000	Inparanoid score	I1841
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55980
OrthoDB	1	1.010	-	-		D360753at33208
OrthoFinder	1	1.000	-	-		FOG0004942
OrthoInspector	1	1.000	-	-		oto18169
orthoMCL	1	0.900	-	-		OOG6_102393
Panther	1	1.100	-	-	LDO	PTHR13090
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4328
SonicParanoid	1	1.000	-	-		X4031
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940