DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8067 and BUD23

DIOPT Version :9

Sequence 1:	NP_001260960.1	Gene:	CG8067 / 36552	FlyBaseID:	FBgn0033891	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_006715910.1	Gene:	BUD23 / 114049	HGNCID:	16405	Length:	304	Species:	Homo sapiens

Alignment Length:	296	Identity:	68/296 - (22%)
Similarity:	103/296 - (34%)	Gaps:	104/296 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 EIGFRLADRVFDI--KREFKAA--ADIGCSRGYLSRHILAESVEQLTLTDTSATMLEQA------ 112
            :|..|:|.|..::  ..|.|..  .||||..| ||...|::........|.|..||::|
Human    57 DIQTRMAGRALELLYLPENKPCYLLDIGCGTG-LSGSYLSDEGHYWVGLDISPAMLDEAVDREIE 120

  Fly   113 ---------QGTPGLKMVKLVKDEEQLDFEDNSLDLVISSLSLHWVNDLPGCFVRIKQSLKPDG- 167
                     ||.|               |:..:.|..||..::.|:     |... |:|..|..
Human   121 GDLLLGDMGQGIP---------------FKPGTFDGCISISAVQWL-----CNAN-KKSENPAKR 164

  Fly   168 --VFIASMFG----GDTLYELRSSLQLAELERKGGISPHISPFTQIRDIGSLLNRAGFTMLTIDT 226
              .|.||:|.    |.     |:.|||         .|..|  .|:..|.:...:|||      :
Human   165 LYCFFASLFSVLVRGS-----RAVLQL---------YPENS--EQLELITTQATKAGF------S 207

  Fly   227 DELVIGYPS-----MFEL-------MWDLKGMAEN------------NAAFNRPAHLSRETMLAA 267
            ..:|:.||:     .|.|       .:..:|::||            |..|  |..:||..|:..
Human   208 GGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERF--PLRMSRRGMVRK 270

  Fly   268 SAIY----QELYAKPNEKGIPATFQIIYFVGWKPGP 299
            |..:    :|.:.:...:..|.|    .:.|.|..|
Human   271 SRAWVLEKKERHRRQGREVRPDT----QYTGRKRKP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8067	NP_001260960.1	BioC	58..296	CDD:273953	66/291 (23%)
CG8067	NP_001260960.1	Methyltransf_11	79..170	CDD:285453	25/108 (23%)
BUD23	XP_006715910.1	AdoMet_MTases	38..>117	CDD:302624	19/60 (32%)
		Methyltransf_11	81..184	CDD:285453	31/129 (24%)
		WBS_methylT	227..302	CDD:289366	15/80 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810