Protein Alignment Ctf4 and Ctf4

DIOPT Version :10

• Sequence 1: NP_610921.1
• Gene: Ctf4 / 36551
• FlyBaseID: FBgn0033890
• Length: 895
• Species: Drosophila melanogaster
• Sequence 2: XP_061507487.1
• Gene: Ctf4 / 1269764
• VectorBaseID: AGAMI1_011817
• Length: 995
• Species: Anopheles gambiae
• Alignment Length: 926
• Identity: 367/926 - (39%)
• Similarity: 521/926 - (56%)
• Gaps: 79/926 - (8%)

  Fly     1 MSFLRSALRYAHTNGYTGLLYTPRGEFIITCGTDGDIRHWTCISDDDPRSSCLGEFVMCIAHTGT 65
            |.|.||.:||||..|||.:.|...|..||:.|.|||.|.|..|.||||.:.|:||.|......|.
Mosquito     1 MPFKRSPMRYAHIMGYTSVTYQDDGNCIISVGYDGDFRIWNGIGDDDPPTVCVGEHVWAALQYGD 65

  Fly    66 RLLASTDRNTIHAYTFPEMDSDGILMRFTAPATCLKVSGGYTAAGSEDTTIKVLKGDTAGNETVL 130
            |:|.:||.||:.||.:|.:|.|||..||||..||:..:..:.||||||.|||||..|. |.:..|
Mosquito    66 RVLVATDLNTVQAYKYPSLDKDGIEFRFTAFVTCMAKNKRFIAAGSEDATIKVLSVDD-GEQFEL 129

  Fly   131 EGHTGPILALDLFAERKLLVSVAGDGQLKVWNFEEGKELKTIGGLPKVNSFESASLYGTPHFEPQ 195
            |...||:|::|. :::.||.:..|||:|.:|:.:..:..|||..||||.|||:...:.:|.|||:
Mosquito   130 ENLEGPVLSMDA-SKQDLLAASIGDGKLHIWDMKTKELKKTIHDLPKVKSFEAVVHFSSPTFEPK 193

  Fly   196 SGELLAYAVDNEIVVLNTANWEVAFKLRDDSVSSNYSCCQFSPNGERLAAGTTKGEVSIFDVKKR 260
            .|.||||....|:::|||.:|:|..|..:..:|:..:.|:|||.|:.||||:..|::.|:|.:..
Mosquito   194 KGNLLAYPNGKEVILLNTTSWDVVKKFVNPKLSTTLTVCRFSPMGDYLAAGSESGDICIWDCETG 258

  Fly   261 KAVTVEIPPSDCNAITCLAWNLSGEVEVAFCDATGQLGTV---FLGDAVDTGNGDGLVDDQAELL 322
            |.|..: .|.|.|.||.|.||.....|:|..|..||:|||   |:....|...|..:| ..||..
Mosquito   259 KLVEGD-KPYDANPITKLVWNPKNNGELALSDGNGQVGTVTDIFVEGGEDDAEGADIV-AMAEKE 321

  Fly   323 GDDYEFEAGDDV--------------DTAADD---GDGVSLEQLKRKVMNFADPVDHDDA--SNQ 368
            .||.:.:|.||:              |.:.||   .:.:.||:||.:||.   |....|.  |:.
Mosquito   322 DDDEDDDAFDDLFNAHLKPDERDSENDASGDDEANENCIELEKLKSQVMG---PTQKSDGAMSDA 383

  Fly   369 SLDSSSR-TVPAPVAPQIKLFKQQTAFQPSATPADLEHRYMAWNDVGIVTAHVEPSGDSSIDVEF 432
            ..|...| ||.:......|.:.||..||||:||..|||.|:.:|.||||..|.... ::||:|||
Mosquito   384 GFDDDDRGTVRSERLAVAKSYPQQHPFQPSSTPNSLEHCYLVYNHVGIVRRHATDK-ENSIEVEF 447

  Fly   433 HDASIHHALHISNYNQHNLASVSSGALALA-SNES---SKLVVIALAAAGNKEWSLSLPDCESAE 493
            ||:..||.:|::|:..|.:|.:|...||:| .||.   ||:|.|..||.|.:||:.::|.||...
Mosquito   448 HDSQQHHGIHLNNFLNHTMAGLSETVLAMACPNEDGNPSKIVCINQAAFGKREWTYTMPGCEEII 512

  Fly   494 AVVATRFLVAVATSSSFLRIFTVMGTQREVLTIPGPMVAIAGHEHSLMVVYHSSAPSQTQQHLAA 558
            ||.|:..:|.|||.|..||::|..||||||:.:.||:||:|.:....:|.|| |||:...||::.
Mosquito   513 AVTASDKIVVVATDSRLLRVYTARGTQREVIAVAGPIVALAAYGDHFLVAYH-SAPANEDQHISL 576

  Fly   559 MLVNINGLSLRQEYLPVPLTPGRQLTWFGYSDTGSPSIADNMGLLQLYRRSSNAWFPICDT-MKQ 622
            |:|......||...:.||||.|.::.|.||||.|||::.|..|:|.:|..:||.|.||.:. ..|
Mosquito   577 MIVTCVNFKLRCREVRVPLTAGSEMQWVGYSDRGSPAVYDTAGMLNIYHATSNLWLPIYNAEYLQ 641

  Fly   623 STSVSHNFFVVAVSEKRQIVQAVLCRGTSYPMTNPRPMLQELRMQIPLCDVEVEKSELEDALLRS 687
            :...|.:.|::.|||..|.||.|||||:.||:|.|:|:..|::..:|:||:|.||..|||.|:||
Mosquito   642 TKGASDHLFIIKVSESTQHVQLVLCRGSKYPLTTPKPIPMEVKFALPMCDLESEKECLEDDLVRS 706

  Fly   688 SLMQMDGAEKMQKETAIKLFALACSSECETRARELIESIACTDLLQLAVKYATKRGRIHLSDRLC 752
            ..::::.|:|:.||||:|||||||.:|||.||:||:|:||.:.|:.|.:|||:|..|.||:|.|.
Mosquito   707 LYLKVNDADKLMKETAVKLFALACKNECEQRAKELVETIASSHLIPLVIKYASKIRRYHLADSLA 771

  Fly   753 ELLP--QLEAVQEARKQQTLLGASGIAATIV-----LPMTPTSASQSGPKPKAIELSSAKRGTLK 810
            .|||  |.:.|||.:.:|..:..:   |.||     :.:...:...:.||.|.:.:.:.|
Mosquito   772 PLLPTFQEQEVQEEKLEQESVREN---AAIVNELQHINLEAITKKDTTPKIKPLPVGTKK----- 828

  Fly   811 RLVNSPNMFKAAAASAASRPSTPDI--------TPSPLD--TQENI-FGESESEVPM--GKAT-- 860
                ..|.|:.:.|:|....|:|..        :.:||:  |.:.| |..|.|..|.  .|.|
Mosquito   829 ----PTNPFRKSTAAATDGISSPASSSGHTGANSSNPLEHLTGKAIGFSASRSSSPSVGSKLTSS 889

  Fly   861 --------DHRSPLNS 868
                    |...|.||
Mosquito   890 SVDATGGQDENRPQNS 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctf4	NP_610921.1	WD40	12..256	CDD:475233	107/243 (44%)
		WD40 repeat	16..52	CDD:293791	17/35 (49%)
		WD40 repeat	97..131	CDD:293791	15/33 (45%)
		WD40 repeat	138..173	CDD:293791	11/34 (32%)
		WD40 repeat	181..223	CDD:293791	18/41 (44%)
		WD40 repeat	231..268	CDD:293791	14/36 (39%)
		Mcl1_mid	393..669	CDD:463539	123/280 (44%)
Ctf4	XP_061507487.1	None