Protein Alignment Ctf4 and wdhd1

DIOPT Version :10

• Sequence 1: NP_610921.1
• Gene: Ctf4 / 36551
• FlyBaseID: FBgn0033890
• Length: 895
• Species: Drosophila melanogaster
• Sequence 2: XP_031746722.1
• Gene: wdhd1 / 100493060
• XenbaseID: XB-GENE-1217708
• Length: 1124
• Species: Xenopus tropicalis
• Alignment Length: 1016
• Identity: 291/1016 - (28%)
• Similarity: 464/1016 - (45%)
• Gaps: 149/1016 - (14%)

  Fly     1 MSFLRSALRYAHTNGYTGLLYTPRGEFIITCGTDGDIRHWTCISDDDPRSSCLGEFVMCIAHTGT 65
            |..::..:||.|..|:|.:.:...|.|::|||:|||||.|..:.||||:|..:||.....|....
 Frog     1 MPAIKKNMRYGHPEGHTDVCFAESGNFLVTCGSDGDIRIWESLDDDDPKSISIGEKAYSFALKNG 65

  Fly    66 RLLASTDRNTIHAYTFPEMDSDGILMRFTAPA--TCLKVSGGYTAAGSEDTTIKVLKGDTAGNET 128
            :::.:...|.|..:|||:.:.||||.|||..|  ......|...||||.|..:|||:.:.:..:.
 Frog    66 KVVTAASNNAIQLHTFPDGEPDGILTRFTTNANHVVFNNDGTKIAAGSGDFLVKVLQVEDSSQQK 130

  Fly   129 VLEGHTGPILALDLFAERKLLVSVAGDGQLKVWNFEEGKELKTIGGLPKVNSFESASLYGTPHFE 193
            ...||..|:|::....:...:.|.:.||.:::|...:......:..|.|.|...||.......::
 Frog   131 TFRGHGAPVLSVSFDPKDIYIASASCDGSVRIWKITDQTCEAVLPLLEKCNDVFSAKSICRLAWQ 195

  Fly   194 PQSGELLAYAVDNEIVVLNTANWEVAFKLRDDSVSSNYSCCQFSPNGERLAAGTTKGEVSIFDVK 258
            .:||:.||..|...:.:....:.:.:..|.||.::...:...:||..:.|.||:..|.:..::|
 Frog   196 TKSGKFLAIPVGKTVHLYERDSLKNSCTLSDDFITQPVNIVAWSPCAQYLVAGSVDGCIVAWNV- 259

  Fly   259 KRKAVTVEIPPSDCNAITCLAW--NLSGEVEVAFCDATGQLG---TVFLGD---------AVDTG 309
            ..||....|.......|..|||  ::|   :||:.|..|.||   .|..|:         :.||.
 Frog   260 ATKACLERIKHEKGYTICGLAWHPHMS---QVAYTDNEGNLGLLEDVCQGEGKQPSAKISSSDTK 321

  Fly   310 NGDGLVDDQAELLGDDYEFEAGDDV--DTAADDGDGVSLEQLKRKVMNFADPVDHDDASN----- 367
            :.|.|.|..    |||.:|..||.:  :.|.:|.|..:...|..:..|.....|.||.|:
 Frog   322 DYDELFDGD----GDDEDFLNGDMIGHEGAINDEDDDNFTALTGRQRNRGALFDDDDNSSDVPSL 382

  Fly   368 ------------------QSLDS-----SSRTVPAPVAPQIKLFKQQTAFQPSATPADLEHRYMA 409
                              |:..|     ||...|.|..       ||..||..:||..|.||:|.
 Frog   383 KPTGNENPEVEDDQTSSVQNFTSVASVKSSYNGPMPTL-------QQKPFQSGSTPVHLMHRFMV 440

  Fly   410 WNDVGIVTAHVEPSGDSSIDVEFHDASIHHALHISNYNQHNLASVSSGALALA--SNE--SSKLV 470
            ||.||::..:.:.. |::|||||||.|||||:|::|...|.||.||..|:.||  |.|  :|||.
 Frog   441 WNSVGVIRCYNDEQ-DNAIDVEFHDTSIHHAIHLTNTLNHTLADVSQEAVLLACESTEELASKLQ 504

  Fly   471 VIALAA-AGNKEWSLSLPDCESAEAVVATRFLVAVATSSSFLRIFTVMGTQREVLTIPGPMVAIA 534
            .:..:: ..:|||.:.:|..|:.:|:...:..||.||::..||||:|.|.|:|:|::.||:|.:|
 Frog   505 CLHFSSWDTSKEWIVDMPKGENIQAICLGQGWVACATNALLLRIFSVGGVQKEMLSLFGPVVCMA 569

  Fly   535 GHEHSLMVVYHSSAPSQTQQHLAAMLVNINGLSLRQEYL---PVPLTPGRQLTWFGYSDTGSPSI 596
            ||...|:|||.........|.|...|:.:.  ..:::.|   |:||:....|:|.|::..|:|..
 Frog   570 GHGDQLIVVYQRGMGFDGDQCLGVQLLEMG--KKKKQVLHGDPLPLSRKSYLSWLGFTAEGTPCY 632

  Fly   597 ADNMGLLQLYRRS-SNAWFPICDTMKQSTSVSHNFFVVAVSEKRQIVQAVLCRGTSYPMTNPRPM 660
            .|:.|:::|..|| .:.|.|:|:|.:.....|.:::||.:.|..|.::.:.|:|:.:|.|.|||.
 Frog   633 MDSEGIVRLLNRSLGDTWIPVCNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPA 697

  Fly   661 LQELRMQIPLCDVEVEKSELEDALLRSSLM--QMD---------------GAEKMQKETAIKLFA 708
            :..|...:|.|.:..||.::|:...||.:.  .:|               .|:|||:|..:|:||
 Frog   698 VAVLPFNLPYCQITTEKGQMEEQYWRSQIFTNHLDYLSKHGYECDENVKSEAQKMQQELLMKMFA 762

  Fly   709 LACSSECETRARELIESIACTDLLQLAVKYATKRGRIHLSDRLCELLPQLEAVQEARKQQ----- 768
            |:|..|.|.|..||.|.:. ..::.||:|||::..|:.|:.||.|:..:..|...:.:||
 Frog   763 LSCKLEREFRCMELAEFMT-QPVMSLAIKYASRSKRLILAQRLSEMAQEKAAELASAEQQDDAED 826

  Fly   769 ----TLLGASGIAATIVLPMTPTSASQSGPKP-----------------------KAIELSSAKR 806
                ..|.|.       ...|.|....|..||                       :|:|.:::..
 Frog   827 EDFRRRLNAG-------YSRTATEWGDSRAKPVKQDQCEENNEEEEEEEEETEQEEALESNTSAT 884

  Fly   807 GTLKRLVNSPNMFKAAAASAASRPSTPDITPSPLDTQENIFGESESEVP----MGKATDHRSPLN 867
            ....:...||::.|:.|..::::........|.......|.|.|.....    |||.:  |.|.:
 Frog   885 NPFNKSAKSPDISKSGAILSSNQGRVNPFKVSASQKSPAIAGSSSRSTSILDNMGKFS--RKPSS 947

  Fly   868 S------------VNPFAMKRK-LGDTGVIFGSEKLKLAKK 895
            |            :.|.|.|.| ......:|.|.:.|.|.|
 Frog   948 SGSPSTTKTDSLVIKPLAPKAKPRQGQATLFQSVQAKPAAK 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctf4	NP_610921.1	WD40	12..256	CDD:475233	71/245 (29%)
		WD40 repeat	16..52	CDD:293791	17/35 (49%)
		WD40 repeat	97..131	CDD:293791	10/35 (29%)
		WD40 repeat	138..173	CDD:293791	5/34 (15%)
		WD40 repeat	181..223	CDD:293791	7/41 (17%)
		WD40 repeat	231..268	CDD:293791	9/36 (25%)
		Mcl1_mid	393..669	CDD:463539	103/284 (36%)
wdhd1	XP_031746722.1	WD40	10..293	CDD:238121	83/286 (29%)
		WD40 repeat	17..55	CDD:293791	17/37 (46%)
		WD40 repeat	97..133	CDD:293791	10/35 (29%)
		WD40 repeat	140..175	CDD:293791	5/34 (15%)
		WD40 repeat	189..225	CDD:293791	5/35 (14%)
		WD40 repeat	233..269	CDD:293791	9/36 (25%)
		Mcl1_mid	423..706	CDD:463539	103/285 (36%)
		HMG-box_WDHD1	1008..1069	CDD:438809