DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and SDE3

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_172037.1	Gene:	SDE3 / 837047	AraportID:	AT1G05460	Length:	1002	Species:	Arabidopsis thaliana

Alignment Length:	809	Identity:	214/809 - (26%)
Similarity:	373/809 - (46%)	Gaps:	165/809 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 VFMILREQPIVIGFTIQGEKYVEQHHFMRTEALPKASFNINPYRLSSK------ETFKSKGLPPA 374
            |..:|.|..|....|       ....:.|:...||..|.::.|...|:      .:|::: ||..
plant   161 VVFLLAEDKISSSLT-------SNRPYSRSRRAPKKDFAVDDYVKGSRPSKVVERSFRNR-LPLY 217

  Fly   375 NPPIQVLSALKHEDAQMCLASFDNQYQNYCERGREITQENLTGTLRTLLQVEDIERLQHYLSLKQ 439
            ..|.::...::::           ::.:....|  :|..|.....:|||.:|::          |
plant   218 EIPKEIREMIENK-----------EFPDDLNEG--LTARNYANYYKTLLIMEEL----------Q 259

  Fly   440 SEMELHQFGRELSVKMQMGTTSMSVEDILSPGDDVLIINEKGNPKSAVRKMLENNNNVLELALKD 504
            .|.::..:..| :|.|:.....:|:|   .||                  :.|...:::.   .|
plant   260 LEEDMRAYDME-NVSMKRRGIYLSLE---VPG------------------LAERRPSLVH---GD 299

  Fly   505 FDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNTTYTLIFRPLRAVMRYQ 569
            | ..:|.|.:        |.....|...:..|....|::....:.....|...::.     :|:.
plant   300 F-IFVRHAYD--------DGTDHAYQGFVHRVEADEVHMKFASEFHQRHTAGSVYN-----VRFT 350

  Fly   570 YRALQQLSFTRHSDVQRILFPGEI-PNTPLASGVLQLNNKLISTNPEQMQAVRQIALSPRLKA-- 631
            |..:......:..|...:|.|..: |:  |.||     .::|.|.|       .:.:||.|.|
plant   351 YNRINTRRLYQAVDAAEMLDPNFLFPS--LHSG-----KRMIKTKP-------FVPISPALNAEQ 401

  Fly   632 --------------PYIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVALRLLR 682
                          ||::.||||||||.|:||||.|||..:....:||.|.||:|.|.:..:||
plant   402 ICSIEMVLGCKGAPPYVIHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLL- 465

  Fly   683 AIAKAPQSQPRPLTRIFSANCDRRIDNIDDLLLEYSNMYTVHF-YPAVQAVHQYRIVICTLSLAG 746
             ..:..:.:...:.|:.:|.  |..:.|...::.:.....:.| .|.::|:.:|::|:.|...|.
plant   466 -CLEGVRIKDNEIFRLNAAT--RSYEEIKPEIIRFCFFDELIFKCPPLKALTRYKLVVSTYMSAS 527

  Fly   747 KLSTGGFAANNVYTHVFVDEAAASTEAEVLMGIT--CTLSPTLNLILSGDHKQLGPVLQSQRANE 809
            .|:..|....: :||:.:|||..::|.|.::.::  | |:.|: ::|:||.:|||||:.|:.|..
plant   528 LLNAEGVNRGH-FTHILLDEAGQASEPENMIAVSNLC-LTETV-VVLAGDPRQLGPVIYSRDAES 589

  Fly   810 WGLGLTLFERLLQRKC-YQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHL-RTEAPME 872
            .|||.:..|||.:  | |..|.|.:|    .|:|::|:|.||||:.|.:.::|:|.| .::...:
plant   590 LGLGKSYLERLFE--CDYYCEGDENY----VTKLVKNYRCHPEILDLPSKLFYDGELVASKEDTD 648

  Fly   873 IVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQT 937
            .|....|  :|||..||::|:.:.|......::.|..|..||..|::.:|.|    ...:.:.:.
plant   649 SVLASLN--FLPNKEFPMVFYGIQGCDEREGNNPSWFNRIEISKVIETIKRL----TANDCVQEE 707

  Fly   938 DIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVSFVRSFTPK---------LG 993
            |||:|:||:.|..:|:|.|:..:.:::..||||.|||:||.|||:|.||| |.|         ||
plant   708 DIGVITPYRQQVMKIKEVLDRLDMTEVKVGSVEQFQGQEKQVIIISTVRS-TIKHNEFDRAYCLG 771

  Fly   994 FLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEMCRNRKTLVG------EQYLNEDFIT 1052
            ||:|.||.||.::|.||||::||||..:.::.::..::..|.:.....|      |:::.|.|
plant   772 FLSNPRRFNVAITRAISLLVIIGNPHIICKDMNWNKLLWRCVDNNAYQGCGLPEQEEFVEEPF-- 834

  Fly  1053 NKKTGANN---------------VNKGGA 1066
             |:.|::|               :|.|||
plant   835 -KQEGSSNGPQYPPEAEWNNSGELNNGGA 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	182/643 (28%)
		AAA_19	618..687	CDD:289986	31/84 (37%)
		AAA_12	812..1019	CDD:289832	83/217 (38%)
SDE3	NP_172037.1	DEXXQc_Helz-like	396..622	CDD:350796	76/238 (32%)
		AAA_12	592..796	CDD:372468	82/216 (38%)
		Ago_hook	830..957	CDD:371044	9/36 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	139	1.000	Domainoid score	I1552
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D286011at2759
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101029
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.680