DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and LBA1

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_199512.2	Gene:	LBA1 / 834747	AraportID:	AT5G47010	Length:	1254	Species:	Arabidopsis thaliana

Alignment Length:	1041	Identity:	224/1041 - (21%)
Similarity:	372/1041 - (35%)	Gaps:	330/1041 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 LPKASFNINPYRLSSKETFKSKGLPPANP-----------------PIQVLSALKHEDAQMCLAS 395
            :|.....:...::|:::..|.:.|...||                 |:|.    |:|||.
plant   264 VPSEQEQLRARQISAQQINKIEELWKTNPDATLEDLEKPGVDDEPQPVQP----KYEDAY----- 319

  Fly   396 FDNQYQNYCERGREITQENLTGTLRTLLQVE-DIERLQHYLSLKQSEMELHQFGRELSVKMQMGT 459
               ||||               ....|:::| |.:::     :|:|:.:     ..|:|:..:|.
plant   320 ---QYQN---------------VFAPLIKLEADYDKM-----MKESQSK-----ENLTVRWDIGL 356

  Fly   460 TSMSV----------EDILSPGDDVLIINEKGNPKSAVRKMLENNNNVLELALKD---------- 504
            ....|          |..|.|||: |.:...|:   ||....::..:|::|..::
plant   357 NKKRVAYFVFPKEENELRLVPGDE-LRLRYSGD---AVHPSWQSVGHVIKLTAQEEVALELRANQ 417

  Fly   505 ---------FDSILRW-ARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNTTYTLIF 559
                     |.....| :.:.|.|.|::..     ||                  .|.|
plant   418 GVPIDVNHGFSVDFVWKSTSFDRMQGAMKN-----FA------------------VDET------ 453

  Fly   560 RPLRAVMRYQYRAL----QQLSFTRHSDVQRILFPGEIPNTPLASGVLQLNNKLISTNPEQMQAV 620
                :|..|.|..|    .:....|::..:|...||                 |...|..|:.||
plant   454 ----SVSGYIYHQLLGHEVEAQMVRNTLPRRFGVPG-----------------LPELNASQVNAV 497

  Fly   621 RQIALSPRLKAPY-IVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVA------- 677
            :.:     |:.|. ::.||||||||.|....:|.: ..:.:..:||.|.||.|.|::|
plant   498 KSV-----LQKPISLIQGPPGTGKTVTSAAIVYHM-AKQGQGQVLVCAPSNVAVDQLAEKISATG 556

  Fly   678 LRLLRAIAKAPQSQPRPLTRIFSANCDRRIDNIDDLLL-------------------EYSNMYTV 723
            |:::|..||:.::...|:..:......|.:|..:...|                   :|.|:...
plant   557 LKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSELHKLQQLKDEQGELSSSDEKKYKNLKRA 621

  Fly   724 HFYPAVQAVHQYRIVICTLSLAGKLSTGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLN 788
            ......|:..   ::.||...|..|....|.    :..|.:||:..:||.|.|:.:...:.   .
plant   622 TEREITQSAD---VICCTCVGAADLRLSNFR----FRQVLIDESTQATEPECLIPLVLGVK---Q 676

  Fly   789 LILSGDHKQLGPVLQSQRANEWGLGLTLFERLLQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIV 853
            ::|.|||.|||||:..::|...||..:|||||:......:            ||...:|.||.:.
plant   677 VVLVGDHCQLGPVIMCKKAARAGLAQSLFERLVTLGIKPI------------RLQVQYRMHPALS 729

  Fly   854 SLYNNMYYEGHLRT------------EAPMEIVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSV 906
            ...:|.:|||.|:.            :.|..:          ||.  |:.|:...|....:.|..
plant   730 EFPSNSFYEGTLQNGVTIIERQTTGIDFPWPV----------PNR--PMFFYVQLGQEEISASGT 782

  Fly   907 SLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQ------YQRIQEQLNMRNWSQID 965
            |..|..|...|...|...:..|     ::.:.||:|:||:.|      |......|..:.:.:|:
plant   783 SYLNRTEAANVEKLVTAFLKSG-----VVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKEIE 842

  Fly   966 CGSVELFQGKEKHVIIVSFVRSFTPK-LGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQH 1029
            ..||:.|||:||..||:|.|||...: :||||:.|||||.|:|....::::|||:.||:...:..
plant   843 VASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNG 907

  Fly  1030 IIEMCRNRKTLVGEQYLNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKRKNHAKNPVQDAKI 1094
            ::...:..:.||                           :.|.:.|:|.:.:....:....|.::
plant   908 LLTHYKEHECLV---------------------------EGPLNNLKQSMVQFQKPRKIYNDRRL 945

  Fly  1095 FYS------KNELLNLGNECQRKKSELETIFDELPKVPRSVDHDLDEVRSIEAQLKDFQLETKQD 1153
            ||.      .|:....||                |...|                     ...:.
plant   946 FYGGGAGMIGNDNFGSGN----------------PNADR---------------------RGSRG 973

  Fly  1154 AAGTSILVTNAPVTNAAAPSVIPRAGLMKQETPALHSSSVSRPAIRKPTVSAATPVAKSRSPMPE 1218
            .||.|.|.:..|  |.|.|.:.| ||......|.  |.....|    |:...|.|   :|.|:..
plant   974 RAGGSYLPSGPP--NGARPGLHP-AGYPIPRVPL--SPFPGGP----PSQPYAIP---TRGPVGA 1026

  Fly  1219 IPSSSKHPISMSSNPLSTNTERCVNGVLCGIEAVPPSENKTTRSSAYNHIPSGNFRFE--NVRPT 1281
            :|    |.....::.........|.|.|        ...:.|:.:.....||.||..:  |.:|:
plant  1027 VP----HAPQPGNHGFGAGRGTSVGGHL--------PHQQATQHNVGTIGPSLNFPLDSPNSQPS 1079

  Fly  1282 P 1282
            |
plant  1080 P 1080

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	162/693 (23%)
		AAA_19	618..687	CDD:289986	25/76 (33%)
		AAA_12	812..1019	CDD:289832	64/225 (28%)
LBA1	NP_199512.2	DNA2	164..929	CDD:224037	183/827 (22%)
		DEXXQc_UPF1	488..723	CDD:350797	66/262 (25%)
		Med15	<983..>1202	CDD:312941	28/122 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810