DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and AT5G37140

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_198530.1	Gene:	AT5G37140 / 833686	AraportID:	AT5G37140	Length:	692	Species:	Arabidopsis thaliana

Alignment Length:	726	Identity:	154/726 - (21%)
Similarity:	253/726 - (34%)	Gaps:	268/726 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   566 MRYQYR--ALQ----QLSFTRHSDVQRILFPGEIPNTPLASGVLQLNN----------------- 607
            |.:|::  :||    .::.|.::.:...|. .|..|:.|...|||.|.
plant     1 MDHQFKETSLQFGVFLMNLTTNTRIWNALH-NEAANSTLIKSVLQENTLTTEQCVCESGAHGSDR 64

  Fly   608 --------KLISTNPEQMQAVRQIALSPRLKAPYIVFGPPGTGKTSTIVEAIYQLYINRPETHIL 664
                    ||.|:....:.:..:|.......:..:::||||||||.|:...::.|.  :.....:
plant    65 VTNIIRSAKLNSSQEAAILSCLKIRNCNHKHSVKLIWGPPGTGKTKTVATLLFCLL--KLSCKTV 127

  Fly   665 VLAGSNTACDEVALRLLRAIAKAPQSQPRP----------------------------------L 695
            |.|.:|||..||..||| ::.|...|:...                                  |
plant   128 VCAPTNTAIVEVTSRLL-SLFKTSSSEHSTYGLGNIVLSGNQARMGIKENDVLLDVFLDERIGIL 191

  Fly   696 TRIFS--ANCDRRIDNIDDLL--LEYSNMYTVHFYPAVQAVHQ-------------YRIVICTLS 743
            |.:||  :...:|::::.|.|  .|....:.||....|:.:.:             ..|.|.|..
plant   192 TSLFSPTSGWKQRLESLIDFLENTEAKYEHYVHLLKEVERMSEEAEKKKKGADKKPKAIKILTFG 256

  Fly   744 LAGKLSTGGFAAN------NVYTH----------------------------------------- 761
            ...|.:..||:..      :::||
plant   257 EFVKKTFDGFSEELEKGMVDLWTHLPKSFITSENVKSMVTARKALQRVRYFLKENFSRDDFKKGS 321

  Fly   762 ----------------------------------------------------------------- 761

plant   322 LKFDCFNGVSAYCLQILRLLPERFEVSDMLENNDTKTFCLQNADIIFCTASGAADMNPIRTGSVD 386

  Fly   762 -VFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTLFERLLQRKC 825
             :.|||||...|.|.:..:  .||...:.:|.||..||..::.    ||...|.:|||||:
plant   387 LLVVDEAAQLKECESVAAL--QLSGLRHAVLIGDELQLPAMVH----NEAKFGRSLFERLV---- 441

  Fly   826 YQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHLRTEAPMEIVCRFHNWFYLPNATFPI 890
              :.....:..:||      :|.||.|....|..:|.|.::..|.:: ...:...|...|.....
plant   442 --LLGHNKHLLNVQ------YRMHPSISRFPNKEFYGGRIKDAANVQ-ESIYQKRFLQGNMFGSF 497

  Fly   891 MFHSV------FGTTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQY 949
            .|.:|      ||...:.|:.|      |:.|:.:.:.:|  |.::.|:.::..:|::||||.|.
plant   498 SFINVGRGEEEFGDGHSPKNMV------EVAVISEIISNL--FKVSSERRIKMSVGVVSPYKGQV 554

  Fly   950 QRIQEQ-------------LNMRNWSQIDCGSVELFQGKEKHVIIVSFVRS-FTPKLGFLNNERR 1000
            :.|||:             ||:|        ||:.|||.|:.:||:|.||| ...|:|||||.:|
plant   555 RAIQERTTNKYSSLSGLFTLNVR--------SVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQR 611

  Fly  1001 LNVLLSRPISLLILIGNPRTLS-QNSDFQHIIEMCR---------NRKTLVGEQYLNEDFITNKK 1055
            .||.|:|....|.:|||..||: ..|.:..:|...|         :.|.|  ...:||..:.:..
plant   612 ANVALTRARHCLWVIGNETTLALSGSSWAKLISESRTLGCFYDAADEKNL--RDAMNEALLEDVS 674

  Fly  1056 T--GANNVNKG 1064
            |  |:.::..|
plant   675 TSFGSLSIRNG 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	147/695 (21%)
		AAA_19	618..687	CDD:289986	21/68 (31%)
		AAA_12	812..1019	CDD:289832	68/226 (30%)
AT5G37140	NP_198530.1	AAA_11	73..429	CDD:289831	59/364 (16%)
		AAA_19	95..155	CDD:289986	22/62 (35%)
		DNA2	<364..632	CDD:224037	84/302 (28%)
		AAA_12	432..628	CDD:289832	66/224 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810