DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and AT4G05540

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_567301.2	Gene:	AT4G05540 / 825906	AraportID:	AT4G05540	Length:	689	Species:	Arabidopsis thaliana

Alignment Length:	680	Identity:	166/680 - (24%)
Similarity:	267/680 - (39%)	Gaps:	162/680 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 LHQFGRELS-VKMQMGTTSMSVEDILSP---GDDVLII----NEKGNPKSAVRKMLENNNNVLEL 500
            ||.....|| :|..:...:...|..:|.   |:.||.|    |...:.:||:...||...
plant    66 LHNGDGNLSLIKSVLQANTADTEQSVSSRNWGNHVLDIIRSANLNSSQESAILACLETRE----- 125

  Fly   501 ALKDFDSI-LRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNTTYTLIFRPLRA 564
             ::|..|: |.|.   ....|:......:.|| :|.:|.:.|..|     |.||....:...|.|
plant   126 -IRDKTSVKLIWG---PPGTGNTKTVATLLFA-LLSLSCKTVVCT-----PTNTAVVAVASRLLA 180

  Fly   565 VMRYQYRALQQLSFTRHS--DVQRILFPG-------------EIPNTPLASGVLQLNNKLISTNP 614
            :.:       :.|.|.||  .:..|:..|             ::.|..|...:.:| .:|.|.:.
plant   181 LFK-------ESSSTEHSTYGLGNIVLVGNRVRMGIDERGNDDLLNVFLDDRISKL-GELFSPSN 237

  Fly   615 E---QMQAV------------RQIALSPR------------------------LKAP------YI 634
            |   .::||            :.:.||.|                        .:.|      .:
plant   238 EWERSLEAVIDILENAESSYKKYLLLSERKENQETKNILTAFGEFVMKMFLGSKETPEKEEEIIL 302

  Fly   635 VFGP------PGTGKT-STIVEAIYQLYINRPETHILVLAGSNTACDEVALRLLRAIAKAPQSQP 692
            .||.      .|..:| ..|.:.:..||.:.|::.:......|......|||..|...:..|..
plant   303 TFGEFVMEKFDGLSETMKKIQKDMVDLYTHLPKSFLSSNDVKNMIVARQALRQARTFLQEKQGS- 366

  Fly   693 RPLTRIFSANCDRRIDNIDDL--LLEYSNMYTVHFYPAVQAVHQYR--------IVICTLSLAGK 747
                  |:.:|..:...:|.|  |...|..:.:   ||:......|        |:.||.|.|.:
plant   367 ------FTFDCFNKFVCVDCLRTLRLLSKRFEI---PALLMKEDIRTFCLQNAHIIFCTASGAAE 422

  Fly   748 LSTGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGL 812
            ::.....:.::   :.|||||...|.|.:..:  .|....:.:|.||..||..::||:...:...
plant   423 MTAERAGSIDM---LVVDEAAQLKECESVAAL--QLQGLHHAVLIGDELQLPAMVQSEVCEKAKF 482

  Fly   813 GLTLFERL--LQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHLRTEAPMEIVC 875
            ..:|||||  |..|        .:..:||      :|.||.| ||:.||.:.|...::|.:....
plant   483 VRSLFERLDSLGHK--------KHLLNVQ------YRMHPSI-SLFPNMEFYGGKISDAEIVKES 532

  Fly   876 RFHNWFYLPNATFPIMFHSV------FGTTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKL 934
            .:...|...|......|.:|      ||...:.|:.|      ||.||.:.:.:|:  .::.|..
plant   533 TYQKRFLQGNMFGSFSFINVGLGKEEFGDGHSPKNMV------EIAVVSEILTNLL--KVSSETK 589

  Fly   935 LQTDIGIISPYKNQYQRIQEQLNMR------NWSQIDCGSVELFQGKEKHVIIVSFVRS-FTPKL 992
            .:..:|:|||||.|...|||::..:      |...::..||:.|||.|:.:||:|.||| ....:
plant   590 TKMSVGVISPYKAQVSAIQERIGDKYTSVSDNLFTLNVRSVDGFQGGEEDIIIISTVRSNCNGNI 654

  Fly   993 GFLNNERRLNVLLSRPISLLILIGNPRTLS 1022
            |||:|.:|.||.|:|....|.:|||.||||
plant   655 GFLSNRQRANVALTRARHCLWVIGNERTLS 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	166/680 (24%)
		AAA_19	618..687	CDD:289986	19/117 (16%)
		AAA_12	812..1019	CDD:289832	69/221 (31%)
AT4G05540	NP_567301.2	AAA_11	108..475	CDD:289831	81/404 (20%)
		DEXDc	134..>184	CDD:238005	14/65 (22%)
		DNA2	<396..684	CDD:224037	92/315 (29%)
		AAA_12	484..679	CDD:289832	67/217 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810