DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and mov10l1

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_001072624.1	Gene:	mov10l1 / 780080	XenbaseID:	XB-GENE-1217451	Length:	1244	Species:	Xenopus tropicalis

Alignment Length:	812	Identity:	223/812 - (27%)
Similarity:	346/812 - (42%)	Gaps:	203/812 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 MILREQPIVIGFTIQGEKYVEQHHFMRTEALPKASFNINPYRLSSKETFKSKGLPPANPPIQVLS 382
            ::|.....:||..::|....|:..|:    ||...|.....::..:....|:         .|||
Frog   493 LLLCFSDFMIGRCLEGTVESEEESFL----LPPVEFASKQKKVPQEYMSNSR---------TVLS 544

  Fly   383 ALKHEDAQMCLASF------DNQYQNYCER-----------GREITQENLTGTLRTLLQVEDIER 430
            |.....::..|.||      .::.:...|:           |..:|..|....:.|||.:|||
Frog   545 APHKRISRRQLPSFLPLYPIPDRLRKCTEQKMDILALEPCLGEVLTLSNYRKRMSTLLWLEDI-- 607

  Fly   431 LQHYLSLKQSEMELHQFGRE-LSVKMQMGTTSMSVEDI------LSPGDDVLIINEKGNPKSAVR 488
                    .:|||:.:|... :.::.:.|...:.|..|      |:.||.|.:
Frog   608 --------HAEMEIQEFSLSGVCLQKRGGFLLLEVPGIAEGRPFLNQGDKVFL------------ 652

  Fly   489 KMLENNNNVLELALKDFDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNT 553
            |..|.....::..               |::..:.::.          .|.|||...|:...
Frog   653 KYQELTTTAIQFV---------------GLIVEIHEEE----------ITLRVNEELEQSYK--- 689

  Fly   554 TYTLIFRPL-------RAVMRYQYRALQQLSFTRHSDVQRILFPG--EIPNTPLAS--------- 600
                 |.|:       |...|....|::|   ..|.. |::|||.  |:.:..:||
Frog   690 -----FEPMDVEFVVNRVTSRRCQFAVEQ---AEHLG-QKVLFPDTVELQSPQVASRDTSEIDCP 745

  Fly   601 ------GVLQLN----------------------------------------NKLISTNPEQMQA 619
                  |..:.|                                        |.|:  |..|..|
Frog   746 EKKEKTGYQETNQSNPTSRGKNAVYMSDMVTVATQTSTKGSGSPVKKKGQFFNNLL--NNHQKLA 808

  Fly   620 VRQIALSPRLKAPYIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVALRLLRAI 684
            |::|........|||:|||||||||.||:|||.|:|...|::.|||.|.||:|.|.|.|||
Frog   809 VKRILGGECRPTPYILFGPPGTGKTVTIIEAILQIYYALPDSRILVCAPSNSAADLVCLRL---- 869

  Fly   685 AKAPQSQPRPLTRIFSANCDRRIDNIDDLLLEYSNMYTVHFYPA--VQAVHQYRIVICTLSLAGK 747
            .::.|.:|..:.|: :|.| |..:.:.|.:..|..       |.  ::...::||:|.|.|.||.
Frog   870 HQSNQLEPGSMVRV-NATC-RLEETVCDAVRPYCG-------PGEDIRKASRFRIIISTCSSAGM 925

  Fly   748 LSTGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGL 812
            ....|....: :||||||||..::|.|.|:.:......|..:||:||..||||:::|:.:..:||
Frog   926 FYQIGLRVGH-FTHVFVDEAGQASEPECLIPLGLISEVTGQIILAGDPMQLGPIIKSRVSLAYGL 989

  Fly   813 GLTLFERLLQRKCYQVEED-----GSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHLRTEAPME 872
            .::..|||:.|..|..:|:     |:||..:.|:|::|:|||..::.|.:.::|...|...|...
Frog   990 NVSFLERLMARPLYLRDEESYGACGNYNPLLITKLMKNYRSHAALLHLPSKLFYHKELEVCADPA 1054

  Fly   873 IVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQT 937
            :|.:...|..||:..||::||.|.||.|...|:.|..|..|....|.|...|       .|.:.|
Frog  1055 VVNKLLRWDKLPHKGFPLIFHGVRGTEMREGSNPSWFNPSEAVQAMRYCCVL-------AKHVTT 1112

  Fly   938 -----DIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVSFVRSFTPK------ 991
                 |||:|:||:.|.::|:..|...:.|.|..||||.|||:|..|||:|.|||....
Frog  1113 SVSAKDIGVITPYRKQVEKIRTLLRTADLSDIKVGSVEEFQGQEFLVIIISMVRSCEDSLHEDSR 1177

  Fly   992 --LGFLNNERRLNVLLSRPISLLILIGNPRTL 1021
              ||||.:.:|.||.::||.:|||::|||..|
Frog  1178 HLLGFLCSPKRFNVAITRPKALLIVLGNPHVL 1209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	199/689 (29%)
		AAA_19	618..687	CDD:289986	35/68 (51%)
		AAA_12	812..1019	CDD:289832	81/224 (36%)
mov10l1	NP_001072624.1	S1-like	36..>73	CDD:291136
		S1-like	182..234	CDD:291136
		AAA_11	801..982	CDD:289831	74/196 (38%)
		P-loop_NTPase	801..>978	CDD:304359	73/192 (38%)
		DNA2	<914..1213	CDD:224037	113/304 (37%)
		AAA_12	989..1206	CDD:289832	80/223 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920