DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6701 and 4933416I08Rik

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_081976.1	Gene:	4933416I08Rik / 71159	MGIID:	1918409	Length:	280	Species:	Mus musculus

Alignment Length:	290	Identity:	70/290 - (24%)
Similarity:	111/290 - (38%)	Gaps:	89/290 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   419 LRTLL--------QVEDIERLQHYLSLKQSEMELHQFGRELSVKMQMGT-TSMS-----VEDI-- 467
            ||.:|        .|..:||.|           :||.| ||:.|:.||| ||..     :||.
Mouse    25 LRLILGVVYYFQWDVPSVERGQ-----------IHQEG-ELNTKIVMGTVTSFGNDYGWIEDCIF 77

  Fly   468 -----------LSPGDDVLIINEKGNPKSAVRKMLENNNNVLELALKDFDSILRWARNVDGMVGS 521
                       |..||.||...|: :|.|...|..|...:..|...||.||.:   :::...|..
Mouse    78 FSSDAIIGSIPLRTGDKVLAFVEE-DPLSHELKATEVCVSSEEGVSKDADSKV---KDLSVCVSQ 138

  Fly   522 LDKQ-----PRVYF------ARILGVSTQR-----VNITCERQLPDNTTYTLIFRPLRAVMRYQY 570
            :.|.     ...||      ..|||.:.:.     :..:.|:..|..|.:        :|...|.
Mouse   139 VKKNFIYIGDEYYFYLDSISKAILGFTPREGDWLDIEYSVEQGSPKITVH--------SVKATQR 195

  Fly   571 RALQQLSFT---------RHSDVQRILFPGEIPNTPLA-SGVL-QLNNKLISTNPEQMQAVRQIA 624
            |.|:::..|         .|:    |.|..:..|.||. :.:| .:.|.:|..:.:|....|.|:
Mouse   196 RQLEEVCVTSIHKRKGMLNHT----IFFTLDSLNLPLGYTPILGHMVNVVIIQSTQQNYKWRAIS 256

  Fly   625 LSPRLKAPYIV-FGPPGTGKTSTIVEAIYQ 653
            ::|  .:|.:| .||    :.|:.:..:||
Mouse   257 MTP--ISPTVVGIGP----RNSSSLLFLYQ 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	67/277 (24%)
		AAA_19	618..687	CDD:289986	10/37 (27%)
		AAA_12	812..1019	CDD:289832
4933416I08Rik	NP_081976.1	S1-like	60..>103	CDD:291136	12/43 (28%)
4933416I08Rik	NP_081976.1	S1-like	203..254	CDD:291136	11/54 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830