DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6701 and CG6204

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_651229.2	Gene:	CG6204 / 42877	FlyBaseID:	FBgn0039165	Length:	903	Species:	Drosophila melanogaster

Alignment Length:	887	Identity:	192/887 - (21%)
Similarity:	318/887 - (35%)	Gaps:	274/887 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 KYVEQH-HFMRTE---ALPKASFNINPYRLSSK-ETFKSKGLPPANPP-----IQVLSALKHEDA 389
            :||.|| .|..||   ||...:.::..|.||.| :.|:::.|...|..     :.||.:|    .
  Fly    52 EYVMQHTRFSLTELTNALKMPAIDMFLYFLSDKRDLFENQVLATDNVKRVGLFVDVLWSL----C 112

  Fly   390 QMCLASFDNQYQNYCERGREITQENLTGTLRTLLQVE------DIER---LQH--YLSLKQSEME 443
            ::.|..||..:.:...|     |..|...::.|||.:      |.|.   |.|  ::.|:..:..
  Fly   113 ELELGGFDEVFLSAFSR-----QTALLDKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHG 172

  Fly   444 L--HQFGREL---------SVKMQM--------GTTSMSVEDILSPGDDVLI----------INE 479
            |  || |.||         |.|..|        |..|.:|:.::.|..:.|:          ..:
  Fly   173 LLSHQ-GYELVELYKKLAPSFKSDMIDGLEAFTGNFSHNVKGLIYPTLETLLGKDATKAPNEEED 236

  Fly   480 KGNPKSAVRKMLENNNNVLE---LA-LKDFDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQR 540
            :|.....|.|.:....|:|.   || |.:|...||...:||.:     ||.        |:....
  Fly   237 EGLVSDKVVKYVNALRNLLREDFLAPLVEFVQQLRSGTDVDEL-----KQQ--------GLLWSD 288

  Fly   541 VNITCERQLPDNTTYTLIFRP-------------------------LRAVMRYQYRALQQLSFTR 580
            |::|...|..:...::|:|..                         |...:.:....|..:.:|.
  Fly   289 VHLTLNPQFANAQRHSLVFLKVQFTKESKNAYKTWLNSIKSGTLLCLTTSLAFDDLILASVGYTE 353

  Fly   581 HSDVQRILFP---------GEIPNTPLA--------SGVLQLNNKLISTNPEQMQAVRQIA---- 624
            ...::.....         |...|.||.        ...|:::|.|.:.:.|:....|.|.
  Fly   354 PEKLKEDCLSVQIVKQYNIGNAYNRPLIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGRYIVDGQM 418

  Fly   625 -------LSPRLKAPY---------------------------------IVFGPPGTGKTSTIVE 649
                   :.|.:|..:                                 |:.||||||||...|:
  Fly   419 EIPPPAYMKPGVKLSFNMKPFTLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQ 483

  Fly   650 AIYQLYINRPET---HILVLAGSNTACDEVALRLLR---------------AIAK-------APQ 689
            .:..|..|....   .|:||..:|.:.|:..:::.|               .|:|       .|:
  Fly   484 LVNSLIQNAKALGTGPIIVLTYTNNSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPE 548

  Fly   690 SQPRPLTRI-FSANCD--RRIDNIDDLLLEYSNMYTVH--FYPAVQAVHQYRIVICTLSLAGK-- 747
            ..|..|.|| :..||:  .:..|:..|...:......:  ...|.:.::|....|.||.:..:
  Fly   549 LVPPRLKRIWWLVNCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEKLNQVAERIETLRMVFQFF 613

  Fly   748 ---------LSTGGFAANNVYTH------VFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQ 797
                     ::|...|.:|....      |..:|||...||.:   :.|....|.::||.|||||
  Fly   614 LAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEAHI---VACLTPHTEHVILVGDHKQ 675

  Fly   798 LGPVLQSQRANEWGLGLTLFERLL--------------QRKCYQVEEDGSYNASVQTRLI--RNF 846
            |.|...|::..:    ::|||||:              .|.|  :.|  ....|:...|:  .:.
  Fly   676 LQPFSGSRKVPQ----ISLFERLIVAGLPFSRLNLQYRMRSC--ISE--LLVPSIYDELLCSESV 732

  Fly   847 RSHPEIVSLYNNMYYEGHLRTEAPMEIVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNN 911
            :.:.:|..:..|:|:..|.:.|..|                                |.:|:.|.
  Fly   733 KEYEDIRLMSKNLYFVQHNQPEHCM--------------------------------SDMSIGNL 765

  Fly   912 KEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKE 976
            .|..|    :..|..|.:...:...:||.|:|||..|.:.|:..|.....|.:...||:.|||.|
  Fly   766 YEAGV----LAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYRSTVQVASVDSFQGLE 826

  Fly   977 KHVIIVSFVRS-FTPKLGFLNNERRLNVLLSRPISLLILIGN 1017
            .:::::|.||| .:.::|||....|:.|.|||....|.::||
  Fly   827 ANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGN 868

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	165/788 (21%)
		AAA_19	618..687	CDD:289986	24/137 (18%)
		AAA_12	812..1019	CDD:289832	54/223 (24%)
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	53/232 (23%)
		AAA_19	467..>513	CDD:289986	17/45 (38%)
		UvrD_C_2	688..869	CDD:304668	54/221 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740