Protein Alignment CG6701 and helz

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: XP_021325743.1
• Gene: helz / 406550
• ZFINID: ZDB-GENE-040426-2419
• Length: 1864
• Species: Danio rerio
• Alignment Length: 1030
• Identity: 241/1030 - (23%)
• Similarity: 401/1030 - (38%)
• Gaps: 275/1030 - (26%)

  Fly   408 REITQENLTGTLRTLLQVEDIERLQHYLSLKQSEMELHQFGRELSVKMQMGTTSM---------- 462
            :.:|::|....|..||.:|:|.:.:          |:.:|  .:.|.:|:.|:.|
Zfish   440 KTLTRDNYQPRLHDLLYIEEIAQYK----------EVSKF--NIKVNLQLVTSFMLTGISGGAKY 492

  Fly   463 ----------SVEDILSPGDDVLIINEKGNPKSAVRKMLENNNNVLEL-ALKDFDSILRWARNVD 516
                      .:.:.||  :|.|          |.|.::...|:||.| ..|:     |..:|
Zfish   493 AQNGQLFARFKLTETLS--EDTL----------AGRLVMTKVNSVLLLPVFKE-----RMGQN-- 538

  Fly   517 GMVGSLDKQP-----RVY------------FARILGVSTQRVNITCERQLPDNTTYTLIFRPLRA 564
                    ||     |||            |.|:.......:.:..:::|.....:.|...|| .
Zfish   539 --------QPAGAKERVYEALIEEKTKDYIFLRVCKECCDELGLVADQELQVELQFQLNRLPL-C 594

  Fly   565 VMRYQYRALQQLSFTRHSDVQRILFPG-----EIPNTPLASGVLQLNNKLISTNPEQMQAVRQIA 624
            .|.|....::..|         ||||.     .||.:|......||:.:|   |.:|.:|:..|.
Zfish   595 EMHYALDRVRDNS---------ILFPDISLTPTIPWSPNRQWDEQLDPRL---NAKQKEAILAIT 647

  Fly   625 --LSPRLKAPYIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVALRLLRAIAKA 687
              ||..| .|.::.||.|||||.|:.:|:..: :.:||:.:|:...||:|.|......|....:|
Zfish   648 TPLSINL-PPVLIIGPYGTGKTFTLAQAVKHI-LKQPESRVLICTHSNSAADLYIKDYLHPYVEA 710

  Fly   688 PQSQPRPLTRIFSANCDRRIDNIDDLLLEYSNMYTVHF---YPAVQAVHQYRIVICTLSLAG--- 746
            .....||| |::..|  |.:..:..|:.:|..:...||   .|..|.|.::|:|:.|||.:.
Zfish   711 GNPHARPL-RVYFRN--RWVKTVHPLVQQYCLISGAHFTFQMPTRQDVERHRVVVVTLSTSQYLC 772

  Fly   747 --KLSTGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANE 809
              .|..|      ::||:.:||||.:.|.|.:|.:...:..| .::|:|||.||.|.:.|:.|.|
Zfish   773 QLDLEPG------IFTHILLDEAAQAMECETIMPLALAVKST-RVVLAGDHMQLSPFVYSEFARE 830

  Fly   810 WGLGLTLFERLLQRKCYQVEEDGSYNASVQTRLI--RNFRSHPEIVSLYNNMYYEGHLRT---EA 869
            ..|.::|.:||.:.          |.:....|::  .|:|||..|::..::::|||.|..   :.
Zfish   831 RNLHVSLLDRLYEH----------YPSEYPCRILLCENYRSHEAIINYTSDLFYEGKLMASGKQP 885

  Fly   870 PMEIVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNNKEIDVVMDYVKDL-MYFGLNGEK 933
            |       |..||      |:.|.:..|..:..|:|.:..||.|:..:::.|::: ..:.::..|
Zfish   886 P-------HKDFY------PLTFFTARGEDVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGK 937

  Fly   934 LLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVSFVRS-FTPK------ 991
            |.:..||::|||.:|..||:.:|..:..|::....|...|||:..|:.:|.||: .|.|
Zfish   938 LEEGSIGVVSPYADQVFRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAI 1002

  Fly   992 ---------------LGFLNNERRLNVLLSRPISLLILIGNPRTLSQ----NSDFQHIIEMCRNR 1037
                           .|||:|.:.||..::|..||:.::|:|..|..    ...::..|.:|...
Zfish  1003 KRKEQLVEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHEN 1067

  Fly  1038 KTLVG---EQY-----------------LNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKRK 1082
            .:|.|   ||.                 |..:||.......:...:|      |......|.|.|
Zfish  1068 HSLHGITFEQIKIQLEALELKKTYVLNPLAPEFIPRALRSQHPPQQG------PGKHQHSPPKAK 1126

  Fly  1083 NHAKNPVQ--DAKIFYSKNELLNLGNECQRKKSELETIFDELP--------KVPRSVDHDLDEVR 1137
            ....|..:  ..:.|...|..:.:||..|....         |        |.|..|.. ||...
Zfish  1127 GQLANHTEPFPPEGFVQPNAAVLMGNPIQAFTP---------PGAGAPASGKSPSPVQR-LDPGA 1181

  Fly  1138 SIEAQLKDFQLETKQDAAGTSILVTNAPVTNAAAPSVIPRAGLMKQETPALHSSSVSRPAIRKPT 1202
            ||        |.......|..::....||     |.::|.||.
Zfish  1182 SI--------LYVPAVYGGNMVMPMPLPV-----PQLLPWAGY---------------------- 1211

  Fly  1203 VSAATPVAKSRSPM-PEIPSSSKHPISMSSNPLSTNTERCVNGVLCGIEAVPP---SENKTTRSS 1263
                    :||.|| |.|.|......:::..|.::.|    :.||.|.....|   ::.:.|...
Zfish  1212 --------QSRFPMDPRIMSHQAAMYNLNLRPAASRT----SPVLYGFSHASPLGLNQQQNTEKE 1264

  Fly  1264 AYNHIPSGNFRFENVRPTPEEVRRFNGANDQRRARPFREPHGNWSNF-GWSPPPR 1317
            .... ||||.:.: :....|..|..   ..:|:|...:|..|:..:. ..||.|:
Zfish  1265 LLQE-PSGNGKMD-INGKAEHCRLL---TPERKAPELKEKQGDLESVQNKSPEPQ 1314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	175/697 (25%)
		AAA_19	618..687	CDD:289986	23/70 (33%)
		AAA_12	812..1019	CDD:289832	60/234 (26%)
helz	XP_021325743.1	zf-CCCH	171..195	CDD:279036
		AAA_11	635..826	CDD:331082	64/205 (31%)
		AAA_12	833..1044	CDD:315700	60/233 (26%)
		Med15	<1108..>1396	CDD:312941	54/275 (20%)
		Atrophin-1	<1473..1835	CDD:331285

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D286011at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920