Protein Alignment CG6701 and upf1

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_593080.1
• Gene: upf1 / 2542327
• PomBaseID: SPAC16C9.06c
• Length: 925
• Species: Schizosaccharomyces pombe
• Alignment Length: 1051
• Identity: 234/1051 - (22%)
• Similarity: 390/1051 - (37%)
• Gaps: 315/1051 - (29%)

  Fly   196 KRLLLQSDKDFELQSLGCYICQENFEKIEKYEEHVEYHGDESDFQSLKKMKKYPTPIVSLSYQTC 260
            |::.|.|........|.||.|                 |..:.|.......|..|.:|.|..|.|
pombe    87 KQVALHSHSSLSDTVLECYNC-----------------GTRNVFLLGFIPAKAKTVVVLLCRQPC 134

  Fly   261 VDSHYFGFTLKTFRKDLVVDKF---IIVQLRQFYYVYGAQMPLPVNGSGELVFFVDSHVFMILRE 322
            ..:        :..||:..|..   .|:..|||       :|..:....|             .|
pombe   135 ARA--------SIAKDMNWDLTQWQPIISDRQF-------LPWLITPPSE-------------EE 171

  Fly   323 QPIVIGFTIQGEKYVEQHHFMRTEALPKASFNINPYRLSSKETFKSKGLPPANPPIQVLSALKHE 387
            |.:.|..|.|        ..:|.|.|.:...|.|...|.  :..:...||...        |:::
pombe   172 QKLAIPITSQ--------QMVRLEELWRKDPNANLEDLD--KPIEDDSLPSVE--------LRYK 218

  Fly   388 DAQMCLASFDNQYQNYCERGREITQENLTGTLRTLLQVE-DIERLQHYLSLKQSEMELHQFGR-- 449
            ||        :.||               ..|..|:|.| |.::     .||:|:.:.....|
pombe   219 DA--------HAYQ---------------AVLSPLIQAEADYDK-----RLKESQTQKDVVVRWD 255

  Fly   450 ----------ELSVKMQMGTTSMSVEDILSPGDDVLII--NEKGNPKSAVRKMLENNNNVLE--- 499
                      .|..|::.|...:::      ||::.:.  .|...|.|:...:::..|||.:
pombe   256 QAINKRYTAWFLLPKLESGEIRLAI------GDEMKLTYEGELRAPWSSTGYVIKIPNNVSDEVG 314

  Fly   500 LALKDFDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLP-DNTTYTLIFRPLR 563
            |.||..|                                 :|.|.|..... |....:..|..::
pombe   315 LELKRSD---------------------------------KVPIECTHNFSVDYVWKSTSFDRMQ 346

  Fly   564 AVMR-YQYRALQQLSFTRHSDVQRILFPGEIPNT---PLASGVLQLNNKLISTNPEQMQAVRQIA 624
            ..:| :.....:..||..|.     |...:||.:   |.....|.:.| |...|..|.:|||.:.
pombe   347 TALRLFATDGSRLSSFLYHK-----LLGHDIPPSFLKPKLPSDLSVPN-LPKLNASQSEAVRAVL 405

  Fly   625 LSPRLKAPYIVFGPPGTGKTSTIVEAIYQL---YINRPETH--ILVLAGSNTACDEVA------- 677
            ..|.    .::.||||||||.|....:|.|   ...:.::|  :||.|.||.|.|::|
pombe   406 SKPL----SLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPVLVCAPSNVAVDQLAEKIHRTG 466

  Fly   678 LRLLRAIAKAPQSQPRPLTRIFSANCDRRIDNIDDLLLEYSNMYTVHFYPAVQAVHQYR------ 736
            ||::|..||:.:.                |::....|..:..:....|.|.:|.:.:.|
pombe   467 LRVVRVAAKSRED----------------IESSVSFLSLHEQIKNYKFNPELQRLLKLRSENNEL 515

  Fly   737 ------------------------IVICTLSLAG--KLSTGGFAANNVYTHVFVDEAAASTEAEV 775
                                    ::.||...||  ::|...|.:      |.:|||..::|.|.
pombe   516 SIQDEKKLRILVAAAEKELLRAAHVICCTCVGAGDRRISKYKFRS------VLIDEATQASEPEC 574

  Fly   776 LMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTLFERLLQRKCYQVEEDGSYNASVQT 840
            ::.:.....   .::|.|||:|||||:.:::.....|..:|||||:            ...:...
pombe   575 MIPLVLGAK---QVVLVGDHQQLGPVVMNKKVALASLSQSLFERLI------------ILGNSPF 624

  Fly   841 RLIRNFRSHPEIVSLYNNMYYEGHLRT-EAPMEIVCRFHNWFYL-PNATFPIMFHSVFGTTMNTK 903
            ||:..:|.||.:....:|.:|||.|:. ....|.:.|..::.:: |::  |:||::.||....:.
pombe   625 RLVVQYRMHPCLSEFPSNTFYEGTLQNGVTTSERIARHVDFPWIQPDS--PLMFYANFGQEELSA 687

  Fly   904 SSVSLCNNKEID----VVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQ----YQRIQEQLNMRN 960
            |..|..|..|..    :|..:::         ..:|...|||::||..|    .|.:|...:|:.
pombe   688 SGTSFLNRTEASTCEKIVTTFLR---------SNVLPEQIGIVTPYDGQRSYIVQYMQNNGSMQK 743

  Fly   961 --WSQIDCGSVELFQGKEKHVIIVSFVRSFTPK-LGFLNNERRLNVLLSRPISLLILIGNPRTLS 1022
              :..::..||:.|||:||..||:|.|||...: :||:|:.|||||.|:|....:|::|||:.|:
pombe   744 DLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGVIVLGNPKVLA 808

  Fly  1023 QNSDFQHIIEMCRNRKTLVGEQYLNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKRKNHAKN 1087
            :::.:.|.:..|:.:      .||.|..:       |::.|.......|    ::|.|.|
pombe   809 KHALWYHFVLHCKEK------GYLVEGTL-------NSLQKFSLTLTPP----QKPQKFK----- 851

  Fly  1088 PVQDAKIFYSKNELLNLGNECQRKKSELETIFDELPKVPRSVDHDLDEVRSIEAQLK-------- 1144
              :|..:..|.:.:.|.|       |.:...|..||.:..|   ...|..::.||.|
pombe   852 --RDLNVQRSLSPIQNAG-------SAMLPSFSNLPNLYSS---SYLEEWNVFAQYKRRESNATD 904

  Fly  1145 --DFQLETKQD 1153
              ||:.:...|
pombe   905 FEDFRSQVGDD 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	165/692 (24%)
		AAA_19	618..687	CDD:289986	28/80 (35%)
		AAA_12	812..1019	CDD:289832	65/219 (30%)
upf1	NP_593080.1	UPF1_Zn_bind	44..193	CDD:286500	32/158 (20%)
		DNA2	66..839	CDD:224037	214/952 (22%)
		P-loop_NTPase	392..>597	CDD:304359	56/233 (24%)
		AAA_12	608..805	CDD:289832	65/219 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I3589
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810