Protein Alignment CG6701 and SPBC29A10.10c

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_596055.1
• Gene: SPBC29A10.10c / 2540523
• PomBaseID: SPBC29A10.10c
• Length: 1944
• Species: Schizosaccharomyces pombe
• Alignment Length: 1550
• Identity: 300/1550 - (19%)
• Similarity: 525/1550 - (33%)
• Gaps: 517/1550 - (33%)

  Fly    45 PRKPTVPWEREL---MGSFLLEMARLQV------ISAQTEWYVDKAKMRKLF--------EVHLN 92
            |:|..:|::.:.   :..|:...:.:.:      :||||:...:....|.:|        |:...
pombe   531 PKKVDIPFKSDFENALNGFVATFSEMLIQTQCWHLSAQTQLVSNPLTFRGIFSLVFSPILEISTG 595

  Fly    93 ALPNSSEIRQKLSSQGATNIGSLLHRTNFLINTPRGN-----PNYRIKNFS----LMDFRKEKFN 148
            ::.....|  .||......||.|| |:.| .||...:     ...:::||.    ::.|.|...|
pombe   596 SISIIKSI--SLSDSVVDTIGELL-RSQF-SNTLNSSCYVLLQWLKVRNFGGAKHIVYFNKLIIN 656

  Fly   149 LLDEQHRLRGIASTTDVPGGAPAEGNKPIIEEYKLDTDVKPTLLKFQKRL--------------- 198
            .:.:.  :.|:.|..               ..:....:.|.:|..|.:.|
pombe   657 TIFDS--VDGLTSKD---------------ATFAKQVEKKESLKNFWESLWKFFTHFFIVLPTWP 704

  Fly   199 ---------LLQSDKDFELQSLGCYICQENFEKIEKYEEHVEYHGDESDFQSLKKMKK------- 247
                     |::...||      |.:....||::..:    .:...::|.:.:....|
pombe   705 VHDKDNLVDLMRDTLDF------CDMLINIFEEVNGF----IFGLSDNDIKIVSANDKGSALAMC 759

  Fly   248 YPTPIVSLSY-QTCVDSHYFGFTLKTFRKDLVVDKFIIVQLRQFYYVYGAQMPLPVNGSGELVFF 311
            ....:|::|| ....||......:|...|.|.:.|.:             :.|:..|       .
pombe   760 IADSLVTVSYWLKLTDSSLLTSVVKVICKMLKICKKL-------------ECPISQN-------V 804

  Fly   312 VD-SHVFMILREQPIVIGFTIQGEKYVEQHHFMRTEALPKASFN-INPYR----------LSSKE 364
            :| .|...|..::..::.||.:.:.::....::..:.|..:.|| .|...          ||..:
pombe   805 IDIIHRASITSDEQTILTFTEREDLFISLTPYLSEDVLNHSPFNDTNTLETKLQSDDRGLLSKDQ 869

  Fly   365 TFK-SKGLPPAN---------PPIQVLSALK--HEDAQMCLASFDNQYQNYCERGREITQENLTG 417
            |.. :|.||.:|         || :.:||.|  :.:||      .:|..|:.:..:|.||.
pombe   870 TIGIAKKLPESNISTSNHFLLPP-KAISASKAINRNAQ------KSQNLNFLKSKQETTQR---- 923

  Fly   418 TLRTLLQVEDIERLQHYLSLKQSEMELHQFGRELSV-----KMQMGTTSMSVEDILSPGDDVLII 477
             :|...:|.......|......|:..:.:..::|..     |..:..||.|..   :|.|.
pombe   924 -IRESAKVPRTSAGNHLSEKLNSDNHIPKALQKLDSADPIRKPSLLHTSKSYS---NPDDK---- 980

  Fly   478 NEKGNPKSAVRKMLENNNNVLELALK------------------DFDSI----------LRWARN 514
            |...:.:.......|::|.:..||.:                  ||||:          ||....
pombe   981 NTSTSDEDTSESEEESSNGLFSLAREANSHASKSLPQRRQIQFLDFDSLKTKNVVHPTQLRRNTQ 1045

  Fly   515 VDGMVGSLDKQPRV--YFARILG-------VSTQRVNITCER---QLPDNTTYTLIFRPL----- 562
            ....:..|...|.|  ::..|||       .|...|.:.|.:   ...|:..|..:|:|:
pombe  1046 QSAQLARLRLNPDVQEFYKVILGWNPLADSFSASNVEMQCVQAKFTYNDSNAYEKVFKPMLFHEC 1110

  Fly   563 -----RAVMRYQYRALQ-----------------------QLSFTRHSDV--------------- 584
                 .||...||..:.                       ::||...:|:
pombe  1111 WAQVKSAVEEKQYPPIDLILNTRSTVDNFVDIYFTSCSPTEVSFLSDTDICLLSKSQSSGDTNNP 1175

  Fly   585 -----------------------------------QRILFPGE-----------------IPNTP 597
                                               ..|.|..:                 :.:.|
pombe  1176 KSFQLCKIQSISRKKESLELCLRMNIESIDLQEYAPNIRFTAQKLFNATTSLREFAALKSLRHLP 1240

  Fly   598 LASGVLQLN-NKLIS--TNPEQMQAVRQIALS-PRLKAPY---------IVFGPPGTGKTSTIVE 649
            |:..:|..| .:|.|  |:.::.:.::...:: |:..|.|         ::.||||||||.||:.
pombe  1241 LSQRILDANVTRLPSNFTDDKKQKIMKSYGVNEPQAYAIYASSVNDGFTLIQGPPGTGKTKTILG 1305

  Fly   650 AI--------YQLYINRP-------ETHILVLAGSNTACDEVALRLLRAI--------------- 684
            .|        ..|..|.|       :..||:.|.||.|.||:.||:...:
pombe  1306 MIGAVLTSSSQGLQFNVPGQTRKTSKNKILICAPSNAAIDEILLRIKAGVYDHEGIKFFPKVIRV 1370

  Fly   685 --------------AKAPQSQPRPLTRI-------FSANCDRRIDNI--------DDL------- 713
                          .:....:...||.:       .|::..::.|:|        :||
pombe  1371 GFGDSISVHAKEFTLEEQMIKQMELTNLKKDQEANNSSDTRKKYDSIIKKRDSLREDLEKFRSTG 1435

  Fly   714 ------------------LLEYS-------------NMYTVHFYPAVQAVHQYRIVICTLSLAGK 747
                              :||.|             |:..:......|.:.:..||..|||.:|.
pombe  1436 KNSSILEAQLREITKQKNMLEQSLDDMRERQRSTNRNLDVLKKQIQNQLLQEADIVCATLSASGH 1500

  Fly   748 --LSTGGFAANNVYTHVFVDEAAASTEAEVLMGIT--CTLSPTLNLILSGDHKQLGPVLQSQRAN 808
              |...|.    .:..|.:||||.:.|...::.:.  |.     :.::.||..||.|.:.|:.:.
pombe  1501 ELLLNAGL----TFRTVIIDEAAQAVELSSIIPLKYGCE-----SCVMVGDPNQLPPTVLSKTSA 1556

  Fly   809 EWGLGLTLFERLLQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHLRTEAPMEI 873
            ::|...:|:.|:     ::...:.:...|:|      :|.:|||....:..:|...| .:.|...
pombe  1557 KFGYSQSLYVRM-----FKQHNESACLLSIQ------YRMNPEISRFPSKFFYNSKL-LDGPNMS 1609

  Fly   874 VCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQT- 937
            ......|...|.... ..|.:|.||...:.|. ||.|.:|...::     |:|     |:|:|.
pombe  1610 AVTSRPWHEDPQLGI-YRFFNVHGTEAFSNSK-SLYNVEEASFIL-----LLY-----ERLIQCY 1662

  Fly   938 -------DIGIISPYKNQYQRIQEQLNMRNWS----QIDCGSVELFQGKEKHVIIVSFVR-SFTP 990
                   .||:::||::|.|:::.|...:..|    .:|..:|:.|||:||.:||.|.|| |.:.
pombe  1663 LNIDFEGKIGVVTPYRSQVQQLRSQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSMSG 1727

  Fly   991 KLGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEMCRNR---KTLVGEQYLNEDFIT 1052
            .:|||.:.|||||.|:|..|.|.::||.:.|.|...|..:||..:.|   :.|...|:.|...|:
pombe  1728 GIGFLQDLRRLNVALTRAKSSLYIVGNSKPLMQEDIFYSLIEDAKTRGVWRDLSANQFKNSKSIS 1792

  Fly  1053 NKKT--GANNVNKGGAAGDQPASGLRQPLKRKNHAKNPVQDAKIFYSKNELLNLGNECQRKKSEL 1115
            |..|  .:||:|.  |:.|.|             .|:|              ::| .|:.|:
pombe  1793 NVSTHLASNNLNL--ASRDTP-------------IKSP--------------SVG-ICEEKQ--- 1824

  Fly  1116 ETIFDELPKVPRSVDHDLDEVRSIEAQLKDFQLETKQDAAGTSILVTNAPVTNAAAPSVIPRAGL 1180
                 |..||.:.  |::|.........:|..:..|:        ..|...|:..|..
pombe  1825 -----EAHKVKKR--HNIDSANLSRGTERDEDIPNKR--------AKNKVSTDQTAAD------- 1867

  Fly  1181 MKQETPALHSSSVSRPAIRKPTVSAATPVAKSRSPMPEIPSSSKHPISMSSNPLS 1235
            .|...|.|..||.|:..:......:....|.|:.|.....:..|..:..|..|.|
pombe  1868 NKVTKPRLDESSSSKQDVLNKIDESEIEQASSKKPGYVEKNKDKGHMKKSKKPKS 1922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	178/884 (20%)
		AAA_19	618..687	CDD:289986	27/122 (22%)
		AAA_12	812..1019	CDD:289832	62/219 (28%)
SPBC29A10.10c	NP_596055.1	SEN1_N	75..784	CDD:289496	46/283 (16%)
		AAA_11	1270..1553	CDD:289831	59/291 (20%)
		AAA_19	1277..1355	CDD:289986	26/77 (34%)
		AAA_12	1560..1756	CDD:289832	62/219 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810