Protein Alignment CG6701 and dna2

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_596499.2
• Gene: dna2 / 2540148
• PomBaseID: SPBC16D10.04c
• Length: 1397
• Species: Schizosaccharomyces pombe
• Alignment Length: 1057
• Identity: 224/1057 - (21%)
• Similarity: 403/1057 - (38%)
• Gaps: 312/1057 - (29%)

  Fly   223 IEKYEEHVEYHGDESDFQSLKKMKKYPTPIVSLSYQTCV-----DSHYFGFTLKTFRKDL----- 277
            :..:.:|..|.|    ..:|:.        |.::.:|.:     |.::...:|...|::|
pombe   476 LHDFFQHALYRG----IDALEN--------VDINLETSIKTYISDIYFADLSLDEIREELDARLP 528

  Fly   278 ----VVDKFII----------VQLRQFY----YVYGAQMPLPVNGSGELVFFVDSHVFMILREQP 324
                :|::::|          :.:.:..    .::..:..|..|        :|:.|.::|.|:|
pombe   529 LLKSIVERYLISKKNDNNNESIHISRLLDIEESIWSPRFGLKGN--------IDATVEVVLTEKP 585

  Fly   325 -----IVIGFTIQGEKYVEQ-HHFMRTEAL-----PKASFNINPYRLSSKETFKSKGLPPANPPI 378
                 :.:...::..:||:. .||.::...     .:...|.|...|...|....|.|..:|..:
pombe   586 ESSSTLTLPLELKTGRYVDNISHFAQSLLYTLLISDRYGINTNQALLCYLENSTIKNLVASNSQL 650

  Fly   379 QVLSALKHEDAQ---------------MC----LASFDNQYQNYCERG---------------RE 409
            :.|...::..||               :|    |.|....:|...::|               ||
pombe   651 RGLIMTRNSLAQHNFRRSLPEMISNRKICDHCSLVSECLFFQKMSDKGVANSNGLTESWNEWMRE 715

  Fly   410 ITQENLTGTLRTLLQVEDIERLQHYLSLKQSEM------ELHQFGRELSVKMQMGTTSMSVEDI- 467
            :..|:|....:....:...|||   |.||:.::      ||..:|:.|.      ...::.|||
pombe   716 VKDEDLEFYKKWEKLLNQEERL---LLLKRGDVLTFDTEELEAYGKTLY------PLYITKEDIV 771

  Fly   468 -LSPGDDVL-----IINEKGNPKSAVRKMLENNNNVLELALKDFDSILRWARNVDGMVGSLDKQP 526
             |...|.|.     .:|:.|.|    |..|.:..:|.|..... |....|         ||.|
pombe   772 CLEIDDRVFHYKFAFLNDNGYP----RNFLHSGFSVGERVFIS-DEHGHW---------SLAK-- 820

  Fly   527 RVYFARILGVSTQRVNITCERQLPDNTTYTLIFRPLRAVMRYQYRALQQLSFTRHSDVQRILFPG 591
                ..|:.:....:.:....:|         ..|...:..:.::. .|:.|..:.| .::.|.|
pombe   821 ----GHIVHIQDSCIEVRTRHRL---------HIPWLKMPNFDFKK-NQVFFGNYED-SKLSFIG 870

  Fly   592 ------EIPNTPLASGVLQLNNKLIST-NPEQMQAVRQIALSPRLKAP----------------- 632
                  .|.....:||:..:...|:|: .|:....:|.:.:  |||.|
pombe   871 SNHTRYRIDKDEFSSGIASIRGTLMSSVLPDAPLIIRDMII--RLKPPKFCNSALIDPEFLKCLN 933

  Fly   633 ----------------YIVFGPPGTGKTSTIVEAIYQLYINRPE------THILV------LAGS 669
                            .::.|.||||||:||...|..|...:.:      ||:.|      |.|
pombe   934 EDQITALKKCHAAEHYSLILGMPGTGKTTTISSLIRSLLAKKKKILLTSFTHLAVDNILIKLKG- 997

  Fly   670 NTACDEVALRLLRAIAKAPQSQPRPLTRIFSANCDRRIDNIDDLLLEYSNMYTVHFYPAVQAVHQ 734
               ||...:||      ....:..||.:.|........|::..|         .|||...|
pombe   998 ---CDSTIVRL------GSPHKIHPLVKEFCLTEGTTFDDLASL---------KHFYEDPQ---- 1040

  Fly   735 YRIVICTLSLAGKLSTGGFAANNVYTHVF---------VDEAAASTEAEVLMGITCTLSPTLNLI 790
              ||.|:       |.|      ||..:|         :|| |:.....:.:|   .|......:
pombe  1041 --IVACS-------SLG------VYHSIFNKRKFDYCIIDE-ASQIPLPICLG---PLQLAEKFV 1086

  Fly   791 LSGDHKQLGPVLQSQRANEWGLGLTLFERLLQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIVSL 855
            |.|||.||.|::::.|.::.||.|:|| :||..|          :....|.|...:|.:.:|.||
pombe  1087 LVGDHYQLPPLVKNSRTSKDGLSLSLF-KLLSEK----------HPEAVTTLRLQYRMNEDINSL 1140

  Fly   856 YNNMYYEGHL----RTEAPMEIVC-RFHNWFYLPNATFPIMF--------HSV--FGTT----MN 901
            .:.:.|.|:|    :|.:..:::. :.|....||:::..:.:        |||  |.|.    :.
pombe  1141 SSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLHWVNKLINPSHSVIFFNTDDILGVE 1205

  Fly   902 TKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDC 966
            :|::..|.|:.|..::...|...:..|:.     |:.|||||.||:|.:.:.:  |::::::|:.
pombe  1206 SKTNNILENHTEAFLIEQAVSSFLERGVK-----QSSIGIISIYKSQVELLSK--NLKSFTEIEI 1263

  Fly   967 GSVELFQGKEKHVIIVSFVRSFTPKL--GFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQH 1029
            .:|:.:||::|.:|::|||||.:..|  ..|.:..||||.|||.....|:.|:..|||.::...|
pombe  1264 NTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLNVALSRAKVKCIMFGSLSTLSSSNIVSH 1328

  Fly  1030 IIEMCRNRKTLVGEQYLNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKRKNHAKNPVQDAKI 1094
            ::::....|.:.   .|||:.|..|             .|:.:|    |:|..:.... ..:||:
pombe  1329 LLKLLEKNKWIF---TLNENDIATK-------------FDENSS----PIKDCSQVAT-TNNAKV 1372

  Fly  1095 FYSKNE-LLNLGNECQR 1110
            ...||: ..|..|.|::
pombe  1373 IIRKNQRFFNSDNLCEK 1389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	165/707 (23%)
		AAA_19	618..687	CDD:289986	25/113 (22%)
		AAA_12	812..1019	CDD:289832	63/227 (28%)
dna2	NP_596499.2	Dna2	385..579	CDD:285859	16/122 (13%)
		DNA2	444..1352	CDD:224037	213/1013 (21%)
		Cas4_I-A_I-B_I-C_I-D_II-B	<558..689	CDD:294426	24/138 (17%)
		P-loop_NTPase	932..>1096	CDD:304359	48/205 (23%)
		AAA_12	1118..1316	CDD:289832	56/214 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810