DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6701 and SPCC737.07c

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_588369.1	Gene:	SPCC737.07c / 2539412	PomBaseID:	SPCC737.07c	Length:	660	Species:	Schizosaccharomyces pombe

Alignment Length:	741	Identity:	179/741 - (24%)
Similarity:	289/741 - (39%)	Gaps:	197/741 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 LKHEDAQMCLASFDNQYQNYCERGREITQENLTGTLRTLLQVEDIERLQHYLSLKQSEMELHQ-- 446
            :...:.|:||.  ::..|.:.:|..|...|....      :|::.|:     |:|:..:.:.|
pombe     1 MSSSNEQICLD--EDWIQKFGDREIEFVDEAQKS------EVDETEK-----SIKRFPLSVLQRK 52

  Fly   447 ---------------FGRELSVKMQMGTTSMSVEDI----LSPGDDVLIINEKGNPKSAVRKMLE 492
                           ||.:..:..:......:.|::    .||||.|.|..:..:.|    |...
pombe    53 GLALINLRIGVVKTGFGGKTIIDFEKDPAFSNGEELPANSFSPGDVVSIRQDFQSSK----KKRP 113

  Fly   493 NNNNVLELALKDFDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQLPDNTTYTL 557
            |..::                :|:|:|      .||:...|      .|.:..|..:|.:.|...
pombe   114 NETDI----------------SVEGVV------TRVHERHI------SVALKSEEDIPSSVTRLS 150

  Fly   558 IFRPLRAVMRYQYRALQQLSFTRHSDVQRILFPGEIP--------------------NTPLASGV 602
            :   ::.|.|..|..:      ||:.::   |...||                    :..|...:
pombe   151 V---VKLVNRVTYERM------RHTMLE---FKRSIPEYRNSLFYTLIGRKKADVSIDQKLIGDI 203

  Fly   603 LQLNNKLISTNPEQMQAVRQIALSPRLKAPYIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLA 667
            ...|.:|   |..|.:||:   .|..:|...::.||||||||.|:||.|.||.:.  ...|||..
pombe   204 KYFNKEL---NASQKKAVK---FSIAVKELSLIHGPPGTGKTHTLVEIIQQLVLR--NKRILVCG 260

  Fly   668 GSNTACDEVALRLLRA-IAKAPQSQP-RPLTRIFSANCD---RRIDNID---------DLLLE-- 716
            .||.|.|.:..||..: |.......| |.|..|...:.|   |..||.|         |:.|.
pombe   261 ASNLAVDNIVDRLSSSGIPMVRLGHPARLLPSILDHSLDVLSRTGDNGDVIRGISEDIDVCLSKI 325

  Fly   717 ------------YSNMYTV----HFYPA---VQAVHQYRIVICTLSLAGKLSTGGFAANNVYTHV 762
                        |.|:..:    ..|.|   ...|...::|.|||..||.....|    ..:..|
pombe   326 TKTKNGRERREIYKNIRELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKG----QRFDAV 386

  Fly   763 FVDEAAASTEAEV---LMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTLFERLLQR- 823
            .:|||:.:.|.:.   |:|:.       .:||:|||.||.|.:||:|..     :::||||::.
pombe   387 IIDEASQALEPQCWIPLLGMN-------KVILAGDHMQLSPNVQSKRPY-----ISMFERLVKSQ 439

  Fly   824 ----KCYQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHL--RTEAPMEIVCRFHNWFY 882
                ||:         .::|      :|.|..|....::.:|:..|  ..|....::....|...
pombe   440 GDLVKCF---------LNIQ------YRMHELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEE 489

  Fly   883 LPNATFPIMFHSVFGTTMNTKSSV--------SLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDI 939
            ......||.|:...|.......|.        |..|:.|..:|..::..|:..||..:     ||
pombe   490 TELTDSPIYFYDTLGNYQEDDRSEDMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAK-----DI 549

  Fly   940 GIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVSFVRS-FTPKLGFLNNERRLNV 1003
            .:::||..|...|::.|..:. .:::.|||:..||:||..||.|.||| ...::|||..:|||||
pombe   550 AVVTPYNAQVALIRQLLKEKG-IEVEMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNV 613

  Fly  1004 LLSRPISLLILIGNPRTLSQNSDFQH 1029
            .::||...|.:||:..|:...|:|.|
pombe   614 AITRPKRHLCVIGDSNTVKWASEFFH 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	172/701 (25%)
		AAA_19	618..687	CDD:289986	28/69 (41%)
		AAA_12	812..1019	CDD:289832	59/222 (27%)
SPCC737.07c	NP_588369.1	TIGR00376	33..651	CDD:273041	172/701 (25%)
		AAA_19	227..275	CDD:289986	23/49 (47%)
		AAA_12	429..629	CDD:289832	59/220 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810