DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6701 and Y53F4B.10

DIOPT Version :9

Sequence 1:	NP_001188923.1	Gene:	CG6701 / 36550	FlyBaseID:	FBgn0033889	Length:	1333	Species:	Drosophila melanogaster
Sequence 2:	NP_001366964.1	Gene:	Y53F4B.10 / 190212	WormBaseID:	WBGene00013157	Length:	471	Species:	Caenorhabditis elegans

Alignment Length:	467	Identity:	94/467 - (20%)
Similarity:	165/467 - (35%)	Gaps:	112/467 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SEIRQKLSSQGATNIGSLLHRTNFL--------INTPRGNPNYRIKNFSLMDFRKEKFNLLDEQH 154
            |::.:.|:|.  .||.|:.|:.:.:        :|:.....|...|..|    .|.|..:|.::|
Worm    18 SKLLRGLNSD--NNIQSITHKVSEMKLDTVSVPVNSKFVPNNLESKTIS----AKLKDPILSDRH 76

  Fly   155 RLRGIASTTDVPGGAPAEGNKPIIEEYKLDTDVKPTLLKFQKRLLLQSDKD----FELQSLGC-- 213
                                 |..:.|....:|:.......|||||.::.|    |..:::.|
Worm    77 ---------------------PFEDYYHDQQNVEQNSENPVKRLLLNTNLDDIQAFRNETIPCMK 120

  Fly   214 -------------------YICQENFEKIEKYEEHVEYHGDES--DFQSLKKMKKYPTPIVSLSY 257
                               :.|  ..:..:.|..:|...|..|  .|...|::.....|.:..:.
Worm   121 KPGRCHMRIPADSQRPPLSFFC--GAKPSQPYALYVVAQGGTSLKCFSVFKELPADDRPDLFSAD 183

  Fly   258 QTCVDSHYFGFTLKTFRKDLVVDKFIIVQLRQFYYVYGAQMPLPVNGSGEL-----VFFVDSHVF 317
            .:|     |.:.:.:.|:.:|.| |:|..|   ..|:..::...|.....|     |..::||.:
Worm   184 LSC-----FSYDILSERQAVVSD-FLIGDL---IIVFSLEVRYGVPPDSYLRDSTHVLKLESHKY 239

  Fly   318 MILREQPIVIGFTIQGEKY-VEQHHFMRTEALPKASFNINPYRLSSKETFKS-KG-----LPPAN 375
            ..:.:..:|.....|.|.: |.|.||...:.|...:..:.|..:.:|...:| :|     ||.|.
Worm   240 WSIEKFAVVQRCVTQPEPFSVHQSHFKADKRLILVNNILTPLTVPTKLLGESCRGVVRAFLPQAA 304

  Fly   376 PPIQVLSALK----HEDAQMCLASFDNQYQNYCERGREITQENLTGTLRTLLQVEDIERLQHYLS 436
            |.: .||:||    :|:.:...|...:.::....                  ||.|:|.:.:...
Worm   305 PGL-TLSSLKPGVLYEEVRRRTAHLGSHWEAMSP------------------QVLDLEVVDNGSM 350

  Fly   437 LKQSEMELHQFGRELSVKM--QMGTTSMSVEDILSPGDDVLIINEKGNP--KSAVRKMLENNNNV 497
            |.:...|......|....:  ..||....||.:......|.|....|.|  .:|:||..:.....
Worm   351 LSRLVEECIDVNTEAIATLYEDRGTHPTKVEKVTCGLRTVTIQFTIGTPSYSAAIRKWKKGTRCS 415

  Fly   498 LELALKDFDSIL 509
            ||.|..|..|:|
Worm   416 LETAAGDILSVL 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	24/90 (27%)
		AAA_19	618..687	CDD:289986
		AAA_12	812..1019	CDD:289832
Y53F4B.10	NP_001366964.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900