Protein Alignment CG6701 and znfx-1

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_001367278.1
• Gene: znfx-1 / 174463
• WormBaseID: WBGene00014208
• Length: 2443
• Species: Caenorhabditis elegans
• Alignment Length: 1112
• Identity: 214/1112 - (19%)
• Similarity: 372/1112 - (33%)
• Gaps: 377/1112 - (33%)

  Fly   115 LLHRTNFLINTPRGNPNYRIKNFSLMDFRKEKFNLLDEQHRLRGIASTTDVPGGAP-AEGNKPII 178
            |:|.:..:.     .||::....|.....:|| .|:...:.||.:|:......|.| ..|.....
 Worm   919 LVHGSKIIF-----RPNFQQAEKSEYQISEEK-KLMKTYNELRSLAACARYTKGKPIPRGVDDDD 977

  Fly   179 EEYKLDTDVKPTLLKFQKRLLLQSDKDFELQSL---------GCYICQENFEKIEKY-------- 226
            |:|:..          :.|.|.:.|.|.|.:.|         |..|...|..:|.|.
 Worm   978 EDYEFS----------KSRELSKEDIDLEYRQLQEPIFRPLVGVDIKDSNLIQINKKWYNVSRLL 1032

  Fly   227 -EEHVEYHGDESDFQSLKKMKKYPTPIVSLSYQTCVDSHYFGFTLKTFRKDLVVDKFIIVQLRQF 290
             |.|.:|. |||...:.....||...::.....| ..:|.....:||           |:|.|.:
 Worm  1033 DEFHPDYM-DESQRLAFCNTFKYELSLIQGPPGT-GKTHIGVQIVKT-----------ILQNRSY 1084

  Fly   291 YYVYGAQMPLPVNGSGELVFFVDS---HVFMILRE---------QPIVIGFTIQGEK----YVEQ 339
            :.:....:.:....||     :|:   .::.::..         :|.:|.|   |.|    |:::
 Worm  1085 WKITEPILVVCFTNSG-----LDNLLERIYQMIENDEELSKDNGRPKIIRF---GSKCDSNYLKR 1141

  Fly   340 HHFMRTEALPKASFNINPYRLSSKETFKSKGLPPANPPI-QVLSALKHEDAQMCLASFDNQYQNY 403
            .:.||.:..               |.:|||....|...: :..:|.:|:...:.::|    |..:
 Worm  1142 QNVMRQDVY---------------EQYKSKVSDGAQKKMSKAGAARRHKADNLAISS----YTLF 1187

  Fly   404 CERGREITQENLTGTLRTLLQVEDIERLQHYLSLKQSEMELHQFGRELSVKMQMGTTSMSVEDIL 468
            |.|.:             ||..|.:.|:..    ...:||:.||..:     .:.|..:.    |
 Worm  1188 CSRNK-------------LLSYEMLSRVMD----PNHQMEIQQFTYD-----HVDTKGIP----L 1226

  Fly   469 SPGDDV---LIINEKGN-PKSAVRKMLENNNNVLELALKDFDSILRWARNVDGMVGSLDKQPRVY 529
            ||.:.:   |:..:.|. .||..:|..:......:|..:|.:.......:.|.....||.:
 Worm  1227 SPDEAIGCWLLERDFGKATKSQTKKAKKPKFQGAQLDSEDENKDYFTVEDSDDEEDELDDE---- 1287

  Fly   530 FARILGVSTQRVNITCERQLPDNTTYTLIFRPLRAVMRYQYRALQQLSFTRHSDVQRILFPGEIP 594
              ::|....:::|:.|...           ..|.||            ...|:|......|.||.
 Worm  1288 --KLLDKLFEKMNLECSGA-----------DILSAV------------HASHADEYYTKGPWEIV 1327

  Fly   595 NTPLASGVL-----------------QLNN-------KLISTNP---EQMQAVRQIALSPRLKAP 632
            .....|.|:                 |:||       .::|:.|   :.:..::.|....|||.
 Worm  1328 QDKRPSVVVLMEKKTKPCNAKFTVDEQINNLVSEIKDMILSSQPVPKKDLNDIKYIFSLARLKR- 1391

  Fly   633 YIVFGPPGTGKTSTIVEAIYQLYINRPETHILVLAGSNTACDEVALRLLRAIAKAPQSQPRPLTR 697
                               :.|||              |.||     .||:|  ..::.||.:..
 Worm  1392 -------------------WSLYI--------------TWCD-----ALRSI--VTENLPRQIRE 1416

  Fly   698 IFSA-----NCDRRIDNIDDLLLEYSNMYTV---------HFYPAVQAVHQYRIVICTLSLAGKL 748
            ...|     |...|:|      .|...|..:         ...|.::.|.. ||:|
 Worm  1417 YREACENFKNAQNRVD------AEIMRMTMIIGATTTGCSRLRPTLEKVGP-RILI--------- 1465

  Fly   749 STGGFAANNVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANE---- 809
                           |:|||...||.:   |:..:|...::::.||||||.|   :...:|
 Worm  1466 ---------------VEEAAEVLEAHI---ISAMISTVEHVVMIGDHKQLRP---NPAVHELGVA 1509

  Fly   810 WGLGLTLFERLLQR--KCYQVEEDGSYNASVQTRLIR-----------NFRSHPEIVSLYNNMYY 861
            :||.:::||||::|  ...|:.:....|.::..::::           |...:|::..:..|:::
 Worm  1510 YGLRISMFERLVERGLPFSQLRQQHRMNLTISDKIVKLSFYDNVTDAENVGLYPDVQGMATNLFF 1574

  Fly   862 EGHLRTEAPMEIVCRFHNWFYLPNATFPIMFHSVFGTTMNTKSSVSLCNNKEIDVVMDYVKDLMY 926
            ..|...|                                .:...||..|..||.:.:..||.|:
 Worm  1575 WSHTSME--------------------------------ESPDEVSWLNKHEISMTVALVKHLL- 1606

  Fly   927 FGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQ----------IDCGSVELFQGKEKHVII 981
                .:.....||.:::.|.     .|:.|..|.::.          |...:|:.|||||:.::|
 Worm  1607 ----KQNYTTNDIVVLATYS-----AQKNLMYREYANVFGSTPDSNVIPVETVDSFQGKERKIVI 1662

  Fly   982 VSFVRSF-----TPKLGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEMCRNRKTLV 1041
            ||.|||.     ...:|||....|:.|.|:|....:.:|||...:..||:..:.|.....|..|:
 Worm  1663 VSLVRSHRGGRENTGIGFLAVANRICVALTRAQHGMYIIGNGAYIMNNSELWNKIVNNLRRSNLI 1727

  Fly  1042 GEQYLNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKRKNHAK-NPVQDAKIFYSKNELLNLG 1105
              :|                              ..|||...|.. ..|:|.:.|.:|:......
 Worm  1728 --EY------------------------------NLPLKCVAHGNIVTVKDPQDFATKSPEGGCM 1760

  Fly  1106 NECQRKK 1112
            .:|..||
 Worm  1761 QKCDTKK 1767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	134/689 (19%)
		AAA_19	618..687	CDD:289986	13/68 (19%)
		AAA_12	812..1019	CDD:289832	50/234 (21%)
znfx-1	NP_001367278.1	DEAD-like_helicase_N	1040..>1133	CDD:421690	19/113 (17%)
		AAA_11	<1328..1499	CDD:404072	47/245 (19%)
		EEXXEc_NFX1	<1434..1534	CDD:350694	31/130 (24%)
		SF1_C_Upf1	1536..1722	CDD:350195	46/227 (20%)
		exchanger_TraA	<1763..2130	CDD:411343	3/5 (60%)
		NF-X1-zinc-finger	2017..>2057	CDD:100116

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910