Protein Alignment CG6701 and AgaP_AGAP006235

DIOPT Version :9

• Sequence 1: NP_001188923.1
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: XP_316302.4
• Gene: AgaP_AGAP006235 / 1276895
• VectorBaseID: AGAP006235
• Length: 1049
• Species: Anopheles gambiae
• Alignment Length: 1040
• Identity: 223/1040 - (21%)
• Similarity: 363/1040 - (34%)
• Gaps: 317/1040 - (30%)

  Fly   253 VSLSYQTCVDSHYFGFTL--KTFRKDLVVDKFIIVQLRQFYYVYGAQMPLPVNGSGELVFFVDSH 315
            :|:....||....|..||  ||:.::|::   :::::....    |.:||         :.....
Mosquito   116 LSMFADICVQKEEFLATLAKKTYGEELLL---VLMKIMNKL----ATLPL---------YETVRQ 164

  Fly   316 VFMILREQPIVIGFTIQGEKYVEQHHFMRTEALPKASFNINPYRLSSKETFKSKGLPPA---NPP 377
            :|.:|.||   ..|..|..||.:|                 |.....|:..|||.:.|.   |..
Mosquito   165 LFGVLLEQ---AHFWEQLLKYFQQ-----------------PAEGEKKKKKKSKIIRPTVARNDM 209

  Fly   378 IQVLSALKHEDAQMCLASFDNQYQNYCERGR---------------EIT------QENLTGTLR- 420
            ::||.....|..:........|...:||:.|               |:|      ||..|..:.
Mosquito   210 MEVLLKFLLEAKRHVAPPLPQQAVEFCEKLRKGAPPDDKAQVELLQELTRDTQTQQEQATKQISI 274

  Fly   421 --TLLQVED----------------IERLQHYLSLKQSEMELHQFGRELSVKMQMGTTSMSVEDI 467
              |:.:::|                .:.:||||     |:.|:....:..:.::.|.......
Mosquito   275 YPTIRELKDGAGPPINLKQNIVKGKYQSVQHYL-----EVHLNLLKEDFLIPLRTGMEKYRKH-- 332

  Fly   468 LSPGDDVLIINEKGNPKS----------AVRKMLENNNN----VLELALKDFDSILRWARNVDG- 517
                     ::.||:.||          .|:.:|.:..|    ..:|.|.|.|...|...|:..
Mosquito   333 ---------VDTKGSGKSFVGENVRVHYPVKLLLPSTVNRRTAKEQLILVDLDPTERGYSNLSAR 388

  Fly   518 ------------MVGSLDKQPRVYFA-------RILGV-----STQRVN-------ITCERQ--- 548
                        |.||:     |.|.       .::.|     :.|.:|       |..|:|
Mosquito   389 YKRLALPNTKRFMNGSM-----VLFCDGPELNELVVAVISNRDAAQLLNGYIYVELIRMEKQREG 448

  Fly   549 -----LPDNTTYTLIFRPLRAV--------MRYQYRALQQL---SFTRHSDVQRILFPGEIPNTP 597
                 :..:....|..|||..:        ....:.||.:|   :|...|.:..:..||:.....
Mosquito   449 GQDQPMGADHGMNLFNRPLLMIESEIFFEPYHQTFNALSRLREDNFPLKSYIVDVTLPGKCLPGY 513

  Fly   598 LASGVLQLNN--------------------KLISTNPEQMQAVRQIALSPRLKAPYIVFGPPGTG 642
            |..|...|.|                    .....|..|..|.| :||:.|..   ::.||||||
Mosquito   514 LYQGGGHLFNYAGIQFDLKKPDEWPTEALTAAAGLNVSQFDAYR-MALTSRFS---LIQGPPGTG 574

  Fly   643 KTSTIVEAIYQLYINRPETHILVLAGSNTACDEV---ALRLLRAIAKAPQSQPRPLTRIFSANC- 703
            ||...:..:..|..|..| .||::..:|.|.|:.   ..|...:|.:.......||...::...
Mosquito   575 KTFIGLRIVETLLANTGE-QILLICLTNHALDQFLCGVTRFTDSIVRMGGQSKHPLLDAYNVKQL 638

  Fly   704 --DRRIDNIDDLLLEYSN-----MYTVHFYPAVQ------------------------------- 730
              |.|||.  .|.:.|.|     :..|..:.|:|
Mosquito   639 QEDERIDR--RLRISYYNAKQEYLKLVERFDALQQEQETLDGMTQAMQECMEELLDASRRLSELS 701

  Fly   731 ------AVHQYRIVICTLSLAGKLSTGGFAANN------VYTH-VFVDEAAASTEAEVLMGITCT 782
                  .:..:|:|..|.:         |||.|      :.|. |.::|||...||.::..:|
Mosquito   702 QLNTLKLIQGFRVVAMTTT---------FAARNRTLLELLRTPIVVIEEAAEVLEAHIVAALT-- 755

  Fly   783 LSPTLNLILSGDHKQLGP-----VLQSQRANEWGLGLTLFERLLQRKCYQVEEDGSYNASVQTRL 842
             ..|...||.||||||.|     ||.|:    :.:.|:||||::..:           .||.|..
Mosquito   756 -RHTAQCILIGDHKQLRPTTSTYVLSSR----YRMDLSLFERMINNR-----------FSVATMT 804

  Fly   843 IRNFRSHPEIVSLYNNMYY----EGHLRTEAPMEIVCRFHNWFYL----PNATFPIMFHSV--FG 897
            ::: |..||:..|...:.|    :.......| .:.....|.|:|    |....|....||  .|
Mosquito   805 VQH-RMRPEMADLLRPLIYPVLDDAETVATRP-NVAGMMRNMFFLTHNYPEGGGPANDSSVGDDG 867

  Fly   898 TTMNTKSSVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKNQ-YQRIQEQLNMRNW 961
            ....:|.::..|.         ::..|..:.|........||.|::.|..| .|.:.|:.|..:.
Mosquito   868 GDEKSKKNIFECR---------FLLGLCEYLLAQGTYTPEDIVILTAYNGQMLQFVAEKKNRPSL 923

  Fly   962 SQIDCGSVELFQGKEKHVIIVSFVRS------FTPKLGFLNNERRLNVLLSRPISLLILIGNPRT 1020
            ..:....::.:||:|..::::|.|||      .|..:|||.:|.|:.|.|||....|.::||...
Mosquito   924 HGVRIAVIDNYQGEESKIVLLSLVRSGTGGNGGTDTIGFLAHENRICVALSRAREGLYIVGNMTL 988

  Fly  1021 LSQNSDFQHIIEMCRNRKTLVGE----QYLNEDFITNKKTGANNVNKGGAAGDQPASGLRQPLKR 1081
            |::.|...|.||.....:..:|:    |.:........|| ..:..:.||:.::...||   |||
Mosquito   989 LAKCSKTWHRIEGKLREQAAIGDSMPLQCVTHGQAVEVKT-PEDFEELGASEERCVCGL---LKR 1049

  Fly  1082  1081
            Mosquito  1050  1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6701	NP_001188923.1	TIGR00376	424..1037	CDD:273041	171/790 (22%)
		AAA_19	618..687	CDD:289986	23/71 (32%)
		AAA_12	812..1019	CDD:289832	54/223 (24%)
AgaP_AGAP006235	XP_316302.4	AAA_11	547..774	CDD:289831	62/245 (25%)
		AAA_19	562..>607	CDD:289986	17/48 (35%)
		UvrD_C_2	785..986	CDD:304668	53/222 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810