Protein Alignment PheRS-m and FDXACB1

DIOPT Version :10

• Sequence 1: NP_477283.1
• Gene: PheRS-m / 36547
• FlyBaseID: FBgn0275436
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_612387.1
• Gene: FDXACB1 / 91893
• HGNCID: 25110
• Length: 624
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 109/538 - (20%)
• Similarity: 191/538 - (35%)
• Gaps: 186/538 - (34%)

  Fly    29 SPSSPPQLEVSGSTYATDGW-------------TNVTP---------KILSYVGANKHLQTDHPL 71
            :|:..||.|...|      |             ::|.|         |...|...:|....:..|
Human   132 TPADKPQREWHNS------WQVVAMAALGGLILSDVYPFSCKAVAGYKCTGYRSQDKSFHVEGAL 190

  Fly    72 SIIRQRIVNYFYGA----YRNQRGNPLFS------VYDQMN----------PVVTVQQNFDNLLI 116
            :.|..|.:. |.|:    :|.:.||..||      :..::|          |:.|:.:.....|.
Human   191 NHIFTRSLP-FEGSQPRIFRIKLGNQWFSFPEPEALVGKLNRGFLEAPSCHPIKTINEKLIAELG 254

  Fly   117 PADHVSRQKS----------------DCYYINQQHLLRAHTTAHQVELISGG----LDNFLVVGE 161
            ....:.|.|.                :|.:::....:..|......|.::||    :::|||
Human   255 KVFPLKRLKCSYPLLPQEGTSVLPFWNCDFLSAAFWISLHEDNSNSESLTGGTSQDVEDFLV--- 316

  Fly   162 VYRRDEIDSTHYPVFHQADAVRLVTKDKLFERNPGLELFEETWSGTLADPKLILPSSKFMDQTKQ 226
                         .|.:...:          :|||.:..||...||....|:.|..|..:
Human   317 -------------SFSELSLL----------KNPGRDGKEEACEGTCGQAKICLRPSLLV----- 353

  Fly   227 PCHTLEAVKLMEHEMKHVLVGLTKDLFGPRIKYRWVDTYFPFTQPSWELEIY-------FKDNWL 284
              |..:.:     |:...|.|....|.||..:...:   .|||.|::...::       .||..|
Human   354 --HVQDVI-----EVPDFLSGSLHILSGPVFQKCHI---LPFTMPAFHETLFILGVNQNLKDGCL 408

  Fly   285 EVLGCGIMRH------------------------EILQRSG------------------------ 301
            :    .::.|                        .:||.:|
Human   409 Q----SLLDHLKGILDSLLTQTLPESSKLSSLVKFVLQSNGKDYMIRVKTHNFSPDCTEDLIIGS 469

  Fly   302 --------VHQSIGYAF-GVGLERLAMVLFDIPDIRLFWSNDSGFLSQFSEKDLHNLPKYKPISH 357
                    :|:...:.| .:.|:.|||:::.|.|.|:.|:.|:.||..|..   ..:..:|..|.
Human   470 VITSATSVIHKDQCFVFVSMNLDLLAMLVWCISDWRMLWTFDNRFLKNFVP---GKIEPFKSHSL 531

  Fly   358 YPQC-TNDLSFWLPQDIEVDAGFSPNDFYDLVRSVAGDMVEQISLVDKFKHPKTGKSSVCFRIVY 421
            ||.| .:|:|||:.|    ..||...:|:.:.|:|:.|.:..|..:.:|:||||.:.|:|:|:.|
Human   532 YPPCYVHDVSFWIDQ----KKGFDELEFHTVARAVSQDTIISIQFLSRFQHPKTQQVSLCYRLTY 592

  Fly   422 RHMERTLTQAEVNEIHKQ 439
            :..::.|||.:|..:..|
Human   593 QTCDKALTQQQVASMQSQ 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PheRS-m	NP_477283.1	pheS_mito	29..452	CDD:129561	109/538 (20%)
FDXACB1	NP_612387.1	BMT5-like	7..176	CDD:463056	9/49 (18%)
		PLN02788	<491..624	CDD:215422	43/127 (34%)