Protein Alignment PheRS-m and MSF1

DIOPT Version :9

• Sequence 1: NP_477283.1
• Gene: PheRS-m / 36547
• FlyBaseID: FBgn0275436
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_015372.2
• Gene: MSF1 / 856160
• SGDID: S000006251
• Length: 469
• Species: Saccharomyces cerevisiae
• Alignment Length: 464
• Identity: 178/464 - (38%)
• Similarity: 261/464 - (56%)
• Gaps: 61/464 - (13%)

  Fly    34 PQLEVSGSTYATD-GWTNVTPKILSYVGANKHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSV 97
            |.:|::|..|.|| ..||||..|:.....:.||:..||:.|:|..|....     |...| .|.:
Yeast    23 PHVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKL-----NSVDN-TFKI 81

  Fly    98 YDQMNPVVTVQQNFDNLLIPADHVSRQKSDCYYINQQHLLRAHTTAHQVEL---ISGGLDN---- 155
            ::...||||..:|||:|..|.||..|.|||.||||:.||||.||:||::|.   |....||
Yeast    82 FNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSG 146

  Fly   156 FLVVGEVYRRDEIDSTHYPVFHQADAVRLVTK-------------DKLFERNPGLE--LFEETWS 205
            ||:..:||||||||.||||||||.:...:..:             :|:.|....:|  |.:|...
Yeast   147 FLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVK 211

  Fly   206 GTLADPKLIL----PSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLTKDLFGPRI--------- 257
            .|:.|..:.|    |..::|...:        |.|....:|..:..:..::|..:|
Yeast   212 ITVDDDTIPLKENNPKQEYMSDLE--------VDLCSQHLKRSIELIVSEVFNKKISSMIKNKAN 268

  Fly   258 ------KYRWVDTYFPFTQPSWELEIYFKDNWLEVLGCGIMRHEILQRSGV--HQSIGYAFGVGL 314
                  |.||::.|||:|.||||:|::::..|||:.|||::|.::|.|:|.  .::||:|||:||
Yeast   269 NTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYKPSETIGWAFGLGL 333

  Fly   315 ERLAMVLFDIPDIRLFWSNDSGFLSQFSEKDLHNLPKYKPISHYPQCTNDLSFWLPQDIEVDAGF 379
            :|:||:||:||||||.||.|..|..||| |.|  :..:||.|.:|....|::||||:|.......
Yeast   334 DRIAMLLFEIPDIRLLWSRDERFSRQFS-KGL--ITSFKPYSKHPGSFRDVAFWLPEDKPDIHQV 395

  Fly   380 SPNDFYDLVRSVAGDMVEQISLVDKFKHPKTGKSSVCFRIVYRHMERTLTQAEVNEIHKQIASAS 444
            ..||..:::|::|||:||.:.|||.|.|||||:.|:|:||.|:.|:|.||.||||.:...:.|..
Yeast   396 HENDLMEIIRNIAGDLVESVKLVDSFTHPKTGRKSMCYRINYQSMDRNLTNAEVNTLQDMVCSKL 460

  Fly   445 VDSFNVQIR 453
            |..::|::|
Yeast   461 VKEYSVELR 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PheRS-m	NP_477283.1	pheS_mito	29..452	CDD:129561	177/461 (38%)
		PheRS_alpha_core	69..334	CDD:238277	114/307 (37%)
		FDX-ACB	356..453	CDD:214893	41/96 (43%)
MSF1	NP_015372.2	pheS_mito	18..468	CDD:129561	177/461 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343919
Domainoid	1	1.000	113	1.000	Domainoid score	I1355
eggNOG	1	0.900	-	-		E1_COG0016
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4788
Inparanoid	1	1.050	311	1.000	Inparanoid score	I474
Isobase	1	0.950	-	0	Normalized mean entropy	S935
OMA	1	1.010	-	-		QHG54668
OrthoFinder	1	1.000	-	-		FOG0003716
OrthoInspector	1	1.000	-	-		oto100057
orthoMCL	1	0.900	-	-		OOG6_102538
Panther	1	1.100	-	-	LDO	PTHR11538
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1439
SonicParanoid	1	1.000	-	-		X3075
TreeFam	1	0.960	-	-
	16	15.740