DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PheRS-m and fdxacb1

DIOPT Version :9

Sequence 1:	NP_477283.1	Gene:	PheRS-m / 36547	FlyBaseID:	FBgn0275436	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001093489.1	Gene:	fdxacb1 / 566022	ZFINID:	ZDB-GENE-030131-8403	Length:	582	Species:	Danio rerio

Alignment Length:	434	Identity:	94/434 - (21%)
Similarity:	166/434 - (38%)	Gaps:	147/434 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 SYVGANKHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSVYDQMNPVVTVQQNFDNLL--IPA- 118
            :::|...|    ||:..:::::       :|.     |.||:    ||.|:.::|..|:  :|.
Zfish   233 NFLGQQSH----HPVKTVQEQL-------HRE-----LKSVW----PVCTINEDFPELVYCLPEM 277

  Fly   119 ------------------------DHVSRQKSDCYYINQQ------HLLRAHTTAHQVELIS--- 150
                                    |....:::||...:.|      :.||.....|..|:..
Zfish   278 LEACDPTLTHSEVYWIKPTDTYVFDQSETKQNDCESTDDQQSFTGSYALRPSLLLHVQEITQNED 342

  Fly   151 ---GGLDNFLVVGEVYRRDEIDSTHYPVFHQADAVRLVTKDKLFERNPGLELFEETWSGTLADPK 212
               |.|  :.|.|.|::|..|.....|.|||...|.:..    .|.:| |..|:::..      .
Zfish   343 FSPGTL--YAVSGLVFQRVPICPIRSPAFHQLLLVGMFP----VESHP-LRCFQDSLE------S 394

  Fly   213 LILPSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLTKDLFGPRIKYRWVD----------TYFP 267
            |::|                    .:...:.|..||.:.:        |::          ||.|
Zfish   395 LLIP--------------------YDVSFEEVQTGLEQQV--------WINSKMLPKFGRITYLP 431

  Fly   268 FTQPSWELEIYFKDNWLEVLGCGIMRHEILQRSGVHQSIGYAFGVGLERLAMVLFDIPDIRLFWS 332
            ....:       .|..|:::                     |..|.|:.||.::|.|.|.||.||
Zfish   432 SISSA-------VDEGLQLV---------------------AVSVNLDHLATLIFGISDWRLLWS 468

  Fly   333 NDSGFLSQFSEKDLHNLPKYKPISHY-PQCTNDLSFWLPQDIEVDAGFSPNDFYDLVRSVAGDMV 396
            .|..||..|   :|.....:.|.|.| |...:|:|||:..:     .:...||:.:||..:..:|
Zfish   469 ADPRFLKHF---ELSPSGPFSPFSLYPPSYLHDISFWMDPE-----NYDELDFHAIVREASCGVV 525

  Fly   397 EQISLVDKFKHPKTGKSSVCFRIVYRHMERTLTQAEVNEIHKQI 440
            :.::|||:|:||..|.:|:|:|:.|:..:|.|:.::|..:..|:
Zfish   526 KNVALVDRFRHPHMGHASLCYRLTYQSSDRALSNSQVLALQNQL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PheRS-m	NP_477283.1	pheS_mito	29..452	CDD:129561	94/434 (22%)
		PheRS_alpha_core	69..334	CDD:238277	59/313 (19%)
		FDX-ACB	356..453	CDD:214893	27/86 (31%)
fdxacb1	NP_001093489.1	DUF2431	8..177	CDD:287341
		class_II_aaRS-like_core	<437..477	CDD:294192	17/60 (28%)
		FDX-ACB	489..582	CDD:214893	27/86 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0016
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810