DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PheRS-m and alpha-PheRS

DIOPT Version :9

Sequence 1:	NP_477283.1	Gene:	PheRS-m / 36547	FlyBaseID:	FBgn0275436	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_572448.1	Gene:	alpha-PheRS / 31740	FlyBaseID:	FBgn0030007	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	77/346 - (22%)
Similarity:	119/346 - (34%)	Gaps:	136/346 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 WTNVTPKILSY--VGA---NKHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSVYDQMNPVVTV 107
            |..:..|..::  :||   ..||   |||..:|......|.     :.|   ||.....|.|.:.
  Fly   201 WDQLKFKAYNFDALGAPPTRGHL---HPLLKVRTEFRQIFL-----EMG---FSEMPTNNYVESS 254

  Fly   108 QQNFDNLLIPADHVSRQKSDCYYIN---------------------------------------Q 133
            ..|||.|..|..|.:|...|.:::|                                       |
  Fly   255 FWNFDALYQPQQHPARDAHDTFFVNHPAKSHKFPQDYLERVKKVHSVGGYGSKGYGYDWKLEEAQ 319

  Fly   134 QHLLRAHTTAHQVELI------SGGLD--NFLVVGEVYRRDEIDSTHYPVFHQADAVRLVTKDKL 190
            ::|||.||||....::      .||..  .:..:.:|:|.:.:|:||...|||.:
  Fly   320 KNLLRTHTTAVSARMLYKLANQEGGFKAAKYFSIDKVFRNETLDATHLAEFHQVE---------- 374

  Fly   191 FERNPGLELFEETWSGTLADPKLILPSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLT-KDLFG 254
                           |.:||                                   |||| .||.|
  Fly   375 ---------------GVIAD-----------------------------------VGLTLGDLIG 389

  Fly   255 PRIKY---------RWVDTYFPFTQPSWELEIYFKD--NWLEVLGCGIMRHEILQRSGVHQSIG- 307
            ...::         .:...|.|:|:||.|:..|...  .|:||...|:.|.|:|...|:.:::.
  Fly   390 TLYEFFRKLGITQLEFKPAYNPYTEPSMEIFCYHPGLAKWIEVGNSGVFRPEMLLPMGLPENVNV 454

  Fly   308 YAFGVGLERLAMVLFDIPDIR 328
            .|:|:.|||..|:.:.|.:||
  Fly   455 IAWGLSLERPTMIKYGINNIR 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PheRS-m	NP_477283.1	pheS_mito	29..452	CDD:129561	77/346 (22%)
		PheRS_alpha_core	69..334	CDD:238277	71/320 (22%)
		FDX-ACB	356..453	CDD:214893
alpha-PheRS	NP_572448.1	PLN02853	4..496	CDD:215458	77/346 (22%)
alpha-PheRS	NP_572448.1	PheRS_alpha_core	224..483	CDD:238277	71/320 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460718
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0016
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11538
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840