DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp1 and RD21B

DIOPT Version :9

Sequence 1:	NP_523735.2	Gene:	Cp1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_568620.1	Gene:	RD21B / 834321	AraportID:	AT5G43060	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	151/366 - (41%)
Similarity:	216/366 - (59%)	Gaps:	42/366 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVMEEWH------------------TFKLEHRKNYQDE---- 73
            ::.:.::.|||::.|:.|:..:.:..:|.|                  .:.:||.|...::
plant     4 LKLSPMILLLAMIGVSYAMDMSIISYDENHHITTETSRSDSEVERIYEAWMVEHGKKKMNQNGLG 68

  Fly    74 TEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAAD 138
            .|:..|.:||.:|...|.:||.:    .:|:||.:.::|||.:.|:|.:..|...| .:.|:.:|
plant    69 AEKDQRFEIFKDNLRFIDEHNTK----NLSYKLGLTRFADLTNEEYRSMYLGAKPT-KRVLKTSD 128

  Fly   139 ESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSE 203
            .      :.:.....||.|||||.:|||..|||||.||||||||:.||:||.:...:|.|:||||
plant   129 R------YQARVGDALPDSVDWRKEGAVADVKDQGSCGSCWAFSTIGAVEGINKIVTGDLISLSE 187

  Fly   204 QNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFN-KGTVGATDRGFTD 267
            |.||||.|.| |.||||||||.||.:|..|||||||..|||:|.|..|..| |.....|...:.|
plant   188 QELVDCDTSY-NQGCNGGLMDYAFEFIIKNGGIDTEADYPYKAADGRCDQNRKNAKVVTIDSYED 251

  Fly   268 IPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGED 332
            :|:..|..:.:|:|. .|:||||:|...:||.||.||: :..|..: |||||:.||:|| |:|:|
plant   252 VPENSEASLKKALAH-QPISVAIEAGGRAFQLYSSGVF-DGLCGTE-LDHGVVAVGYGT-ENGKD 312

  Fly   333 YWLVKNSWGTTWGDKGFIKMLRNKE---NQCGIASASSYPL 370
            ||:|:||||..||:.|:|||.||.|   .:||||..:|||:
plant   313 YWIVRNSWGNRWGESGYIKMARNIEAPTGKCGIAMEASYPI 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/80 (23%)
Cp1	NP_523735.2	Peptidase_C1	154..370	CDD:278538	120/219 (55%)
RD21B	NP_568620.1	Inhibitor_I29	50..109	CDD:214853	17/62 (27%)
		Peptidase_C1	138..353	CDD:278538	120/219 (55%)
		GRAN	377..433	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	233	1.000	Domainoid score	I635
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76699
Inparanoid	1	1.050	260	1.000	Inparanoid score	I973
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0000114
OrthoInspector	1	1.000	-	-		otm2515
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X64
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830