Protein Alignment CtsL1 and Cts8

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001121688.1
• Gene: Cts8 / 680718
• RGDID: 1588248
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 149/345 - (43%)
• Similarity: 206/345 - (59%)
• Gaps: 16/345 - (4%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHN 94
            |...|||.:|. |.||:|...:|..:: ||..:|.::.|||..| ||..:..::.||...:.:||
  Rat     1 MSPVVLLAILC-LGVARATQPSDPSLDSEWQEWKTKYEKNYSLE-EEGQKRAVWEENMKVVKQHN 63

  Fly    95 QRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVD 159
            ..:.:.|.:|.:.:|.:||:...|||::|.....   :.||      |..:...|....|||.||
  Rat    64 IEYDQEKKNFTMELNAFADMTGEEFRKMMTNIPV---QNLR------KKKSIHQPIFRYLPKFVD 119

  Fly   160 WRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMD 224
            ||.:|.||:||:||.|.||||||..||:|||.|||:|.|||||.|||||||...||:||:.|...
  Rat   120 WRRRGYVTSVKNQGTCNSCWAFSVAGAIEGQMFRKTGRLVSLSPQNLVDCSRPEGNHGCHMGSTL 184

  Fly   225 NAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVA 289
            .|.:|:..|||::.|.:||||..:..|.:......|...||:.:.:.:|..| .||||:||:||.
  Rat   185 YALKYVWSNGGLEAESTYPYEGKEGPCRYLPRRSAARVTGFSTVARSEEALM-HAVATIGPISVG 248

  Fly   290 IDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIK 351
            |||||.||:||..|:|.||:|.:..::|.|||||:   |.:..|..|||:|||.|..||..|::|
  Rat   249 IDASHVSFRFYRRGIYYEPRCSSNRINHSVLVVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMK 313

  Fly   352 MLRNKENQCGIASASSYPLV 371
            :.|...|.||||:...||.|
  Rat   314 LARGWNNHCGIATYGFYPRV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	17/58 (29%)
		Peptidase_C1	154..370	CDD:425470	111/218 (51%)
Cts8	NP_001121688.1	Inhibitor_I29	29..87	CDD:214853	17/58 (29%)
		Peptidase_C1A	115..331	CDD:239068	109/216 (50%)