Protein Alignment CtsL1 and cts12

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_695425.1
• Gene: cts12 / 567046
• ZFINID: ZDB-GENE-050208-336
• Length: 349
• Species: Danio rerio
• Alignment Length: 349
• Identity: 154/349 - (44%)
• Similarity: 218/349 - (62%)
• Gaps: 23/349 - (6%)

  Fly    32 RTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQR 96
            |||| ..||....|..|....:....||:.:|.:|..:|.:|:|:..|..|:..|..||.|:|..
Zfish    15 RTAV-FALLVWAPVQVASESEEEAPTEWNLWKKKHEISYDEESEDVHRKTIWETNMQKIWKNNND 78

  Fly    97 FAEGKVSFKLAVNKYADLLHHEFRQLM--------NGFNYTLHKQLRAADESFKGVTFISPAHVT 153
            |:.|...||:|:|||.||...|:::|:        |........|:...:....|||
Zfish    79 FSFGLSMFKMAMNKYGDLTSVEYKRLLGSKIKGTGNRKGKITSAQMLRLNAKRLGVT-------- 135

  Fly   154 LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGC 218
               ::|:|.||.||.|||||:|||||:||:|||:|||.::.:|.|||||||.|||||..||..||
Zfish   136 ---NIDYRAKGYVTEVKDQGYCGSCWSFSTTGAIEGQMYKHTGRLVSLSEQQLVDCSRSYGTYGC 197

  Fly   219 NGGLMDNAFRYIKDNGGIDTEKSYPYEAID-DSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVAT 282
            :|..|.||:.|:.:| .:::..:|||.::| ..|.:.|....|....:..:|.|:|:.:|:||||
Zfish   198 SGAWMANAYDYVINN-ALESSDTYPYTSVDTQPCFYEKNLAMAGISDYRFVPAGNEQALADAVAT 261

  Fly   283 VGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDK 347
            ||||||||||.:.||.|||.|:|.|..|:..||:|.|||||:|::| |.|||::||||||.||:.
Zfish   262 VGPVSVAIDADNPSFLFYSSGIYKESNCNPNNLNHAVLVVGYGSEE-GTDYWIIKNSWGTGWGEG 325

  Fly   348 GFIKMLRNKENQCGIASASSYPLV 371
            |:::|:||.:|.|||||.:.||::
Zfish   326 GYMRMIRNGKNTCGIASYALYPII 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	23/58 (40%)
		Peptidase_C1	154..370	CDD:425470	114/216 (53%)
cts12	XP_695425.1	Inhibitor_I29	41..101	CDD:462410	23/59 (39%)
		Peptidase_C1A	135..347	CDD:239068	114/224 (51%)