back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CtsL1 and tinagl1

DIOPT Version :10

Sequence 1:	NP_523735.2	Gene:	CtsL1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001038442.2	Gene:	tinagl1 / 562116	ZFINID:	ZDB-GENE-060503-240	Length:	471	Species:	Danio rerio

Alignment Length:	284	Identity:	79/284 - (27%)
Similarity:	120/284 - (42%)	Gaps:	65/284 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 HEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAF 181
            :|.:..||| |..|.....|.|:                    |  .|.:....|||:|.:.|||
Zfish   188 NEMQMNMNG-NDHLPSYFNAVDK--------------------W--PGKIHEPLDQGNCNASWAF 229

  Fly   182 SSTG-ALEGQHFRKSGVLV-SLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY 244
            |:.. |.:....:..|.:. .||.|||:.|.|:: .:||.||.:|.|:.::: ..|:.|:..||:
Zfish   230 STAAVASDRISIQSMGHMTPQLSPQNLISCDTRH-QDGCAGGRIDGAWWFMR-RRGVVTQDCYPF 292

  Fly   245 EAIDDS------CHFNKGTVGATDRGFT-----------DIPQG--------DEKKMAEAVATVG 284
            ...:.|      |......||...|..|           ||.|.        :|.::.:.:...|
Zfish   293 SPPEQSAVEVARCMMQSRAVGRGKRQATAHCPNSHSYHNDIYQSTPPYRLSTNENEIMKEIMDNG 357

  Fly   285 PVSVAIDASHESFQFYSEGV-------YNEPQCDAQNLDHGVLVVGFG--TDESG--EDYWLVKN 338
            ||. ||...||.|..|..|:       |::|....::..|.|.:.|:|  .|.||  ..||:..|
Zfish   358 PVQ-AIMEVHEDFFVYKSGIFRHTDVNYHKPSQYRKHATHSVRITGWGEERDYSGRTRKYWIGAN 421

  Fly   339 SWGTTWGDKGFIKMLRNKENQCGI 362
            |||..||:.|:.::.|. .|:|.|
Zfish   422 SWGKNWGEDGYFRIARG-VNECDI 444

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.