Protein Alignment CtsL1 and Ctsll3

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001395605.1
• Gene: Ctsll3 / 498691
• RGDID: 1560071
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 172/345 - (49%)
• Similarity: 217/345 - (62%)
• Gaps: 19/345 - (5%)

  Fly    31 MRTAVLLPLLALLAVAQA----VSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIA 91
            |....||..|.|..::.|    .|| |.|.|||   |.:|.|.| :..||..:..::..|...|.
  Rat     1 MTPIFLLATLCLGMISAAPTHDPSF-DTVWEEW---KTKHGKTY-NTNEEGQKRAVWENNMKMIN 60

  Fly    92 KHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPK 156
            .||:.:.:||..|.|.:|.:.||.:.|||:||.||.....|.::...|.|.|         .:||
  Rat    61 LHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMKVFPEPFLG---------DVPK 116

  Fly   157 SVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGG 221
            :||||..|.||.||:||.||||||||:.|:||||.|||:|.||.||||||||||..:||.||:||
  Rat   117 TVDWRKHGYVTPVKNQGPCGSCWAFSAVGSLEGQVFRKTGKLVPLSEQNLVDCSWSHGNKGCDGG 181

  Fly   222 LMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPV 286
            |.|.||:|:|||||:||..||||||::.:|.:|.....|...||..||. .|..:.:|||||||:
  Rat   182 LPDFAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKYSAAKVVGFMSIPP-SENALMKAVATVGPI 245

  Fly   287 SVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIK 351
            ||.||..|:|||||..|:|.||.|.:.||:|.|||||:|.:..|..|||||||||..||..|:||
  Rat   246 SVGIDIKHKSFQFYKGGMYYEPDCSSTNLNHAVLVVGYGEESDGRKYWLVKNSWGRDWGMDGYIK 310

  Fly   352 MLRNKENQCGIASASSYPLV 371
            |.::..|.|||||.:|||:|
  Rat   311 MAKDWNNNCGIASDASYPIV 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
		Peptidase_C1	154..370	CDD:425470	129/215 (60%)
Ctsll3	NP_001395605.1	Inhibitor_I29	29..87	CDD:214853	20/61 (33%)
		Peptidase_C1	114..329	CDD:425470	129/215 (60%)