Protein Alignment CtsL1 and Ctsrl1

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: Ctsrl1 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 150/345 - (43%)
• Similarity: 207/345 - (60%)
• Gaps: 15/345 - (4%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHN 94
            |..||.:.:|. |.||......|..:: ||..:|.::.|:|..| ||..|..::.||...|..||
  Rat     1 MTPAVFIAILC-LGVASGAPILDPSLDAEWQEWKKKYDKSYSLE-EEELRRAVWEENLKMIKLHN 63

  Fly    95 QRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVD 159
            .....||..|.:.:|::.|....|||::|..|....|::.::..:...|..|        ||.||
  Rat    64 GENGLGKNGFTMEINEFGDTTGEEFRKMMVEFPVQTHREGKSIMKRAAGSIF--------PKFVD 120

  Fly   160 WRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMD 224
            ||.||.||.|:.||:|.:|||||.|||:|.|...:||.|:.||.|||||||...|||||.||...
  Rat   121 WRKKGYVTPVRRQGNCNACWAFSVTGAIEAQTIWQSGKLIPLSVQNLVDCSKPQGNNGCLGGDTY 185

  Fly   225 NAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVA 289
            |||:|:..|||:.:|.:||||..|..|.:|.....|...||..:|:.::..|. ||||:||:|..
  Rat   186 NAFQYVLHNGGLQSEATYPYEGKDGPCRYNPKNSSAEITGFVSLPESEDILMV-AVATIGPISAG 249

  Fly   290 IDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIK 351
            ||||||||:||.:|:|:||.|.:.::.|||||||:   |.|..|:.|||:|||||..||.:|::|
  Rat   250 IDASHESFKFYKKGIYHEPNCSSNSVTHGVLVVGYGFKGNDTGGDHYWLIKNSWGKQWGIRGYMK 314

  Fly   352 MLRNKENQCGIASASSYPLV 371
            :.::|.|.|.|||.:.||.:
  Rat   315 ITKDKNNHCAIASYAHYPTI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
		Peptidase_C1	154..370	CDD:425470	114/218 (52%)
Ctsrl1	NP_001017509.1	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
		Peptidase_C1A	116..332	CDD:239068	113/216 (52%)