DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp1 and ctsv

DIOPT Version :9

Sequence 1:	NP_523735.2	Gene:	Cp1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001004869.1	Gene:	ctsv / 448179	XenbaseID:	XB-GENE-966214	Length:	335	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	179/341 - (52%)
Similarity:	234/341 - (68%)	Gaps:	19/341 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LALLAVAQAVSFA----DVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAE 99
            |.:.|:.....||    |..:: .|:.:|..|:|:|..: ||.:|..::.:|...|..||...:.
Frog     5 LGIAAICLTTVFAAPTTDPALDNHWNLWKNWHKKSYAPK-EEGWRRVLWEKNLRMIEFHNLEHSL 68

  Fly   100 GKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKG 164
            ||.|..|.:|::.|:.:.||||||||  |...|::|       |.||::|.:...|||||||.||
Frog    69 GKHSHSLGMNQFGDMTNEEFRQLMNG--YKNQKKIR-------GSTFLAPNNFESPKSVDWRKKG 124

  Fly   165 AVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRY 229
            .||.|||||.||||||||:||||||||:|.:|.::|||||||||||...||.||||||||.||:|
Frog   125 YVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQY 189

  Fly   230 IKDNGGIDTEKSYPYEAIDD-SCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDAS 293
            :|||||||:|.||||.|.|| .||::.....|.|.||.|:..|.||.:..|||:|||||||:||.
Frog   190 VKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAG 254

  Fly   294 HESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKMLRN 355
            |:|||||..|:|.||:|.:::|||||||||:   |.||.|:.||:|||||...||:.|:|.:.::
Frog   255 HQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKD 319

  Fly   356 KENQCGIASASSYPLV 371
            :.|.||||:|:|||||
Frog   320 RHNHCGIATAASYPLV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
Cp1	NP_523735.2	Peptidase_C1	154..370	CDD:278538	138/219 (63%)
ctsv	NP_001004869.1	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
ctsv	NP_001004869.1	Peptidase_C1	115..334	CDD:306594	138/218 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	306	1.000	Domainoid score	I1354
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H76699
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2161
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0000114
OrthoInspector	1	1.000	-	-		oto103074
Panther	1	1.100	-	-	LDO	PTHR12411
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X64
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160