DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp1 and si:dkey-239j18.2

DIOPT Version :9

Sequence 1:	NP_523735.2	Gene:	Cp1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001274132.1	Gene:	si:dkey-239j18.2 / 321853	ZFINID:	ZDB-GENE-121214-52	Length:	335	Species:	Danio rerio

Alignment Length:	340	Identity:	171/340 - (50%)
Similarity:	229/340 - (67%)	Gaps:	13/340 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEG 100
            ||..|.:.||..|.|....:.:.|:::|.:|.|:|.::.|...|: |:.||..||.:||..::.|
Zfish     5 LLVTLYISAVFAAPSIDIQLDDHWNSWKSQHGKSYHEDVEVGRRM-IWEENLRKIEQHNFEYSLG 68

  Fly   101 KVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGA 165
            ..:||:.:|::.|:.:.||||.|||:.:.       .:.:.:|..|:.|.....|:.||||.:|.
Zfish    69 NHTFKMGMNQFGDMTNEEFRQAMNGYKHD-------PNRTSQGPLFMEPKFFAAPQQVDWRQRGY 126

  Fly   166 VTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYI 230
            ||.||||..|||||:||||||||||.|||:|.|:|:|||||||||..:||.||||||||.||:|:
Zfish   127 VTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYV 191

  Fly   231 KDNGGIDTEKSYPYEAIDD-SCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASH 294
            |:|.|:|:|:||||.|.|| .|.::.....|...||.|||:|:|..:..|||.||||||||||||
Zfish   192 KENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASH 256

  Fly   295 ESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKMLRNK 356
            :|.|||..|:|.|..|.:| |||.|||||:   |.|.:|..||:|||||...|||||:|.|.::|
Zfish   257 QSLQFYQSGIYYERACTSQ-LDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDK 320

  Fly   357 ENQCGIASASSYPLV 371
            .|.||||:.:||||:
Zfish   321 NNHCGIATMASYPLM 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	19/58 (33%)
Cp1	NP_523735.2	Peptidase_C1	154..370	CDD:278538	133/219 (61%)
si:dkey-239j18.2	NP_001274132.1	Inhibitor_I29	28..86	CDD:214853	19/58 (33%)
si:dkey-239j18.2	NP_001274132.1	Peptidase_C1	115..334	CDD:278538	133/219 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2109
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0000114
OrthoInspector	1	1.000	-	-		otm25207
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X64
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.980