Protein Alignment CtsL1 and Ctsr

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_783171.2
• Gene: Ctsr / 290975
• RGDID: 631422
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 143/347 - (41%)
• Similarity: 203/347 - (58%)
• Gaps: 19/347 - (5%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQ 95
            |.:...|.:|.|...:.|::|...:..|||.:|.|:.|:|..| ||..|..::.||...|..||:
  Rat     1 MSSTFFLAILCLGVGSGALAFDPSLDAEWHDWKTEYEKSYTME-EEGHRRAVWEENMKMIKLHNR 64

  Fly    96 RFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQ---LRAADESFKGVTFISPAHVTLPKS 157
            ..:.||..|.:.:|::.||...|||::|.......|::   :|..|           ....|||.
  Rat    65 ENSLGKNGFIMEMNEFGDLTAEEFRKMMVNIPIRSHRKGKIIRKRD-----------VGNVLPKF 118

  Fly   158 VDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGL 222
            ||||.||.||.|::|..|.|||||:.|||:|||.|.|:|.|..||.||||||:...||.||..|.
  Rat   119 VDWRKKGYVTRVQNQKFCNSCWAFAVTGAIEGQMFNKTGQLTPLSVQNLVDCTKSQGNEGCQWGD 183

  Fly   223 MDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVS 287
            ...|:.|:.:|||::.|.:|||:..:..|.:|.....|...||..:|:.::..| |||||:||:|
  Rat   184 PHIAYEYVLNNGGLEAEATYPYKGKEGVCRYNPKHSKAEITGFVSLPESEDILM-EAVATIGPIS 247

  Fly   288 VAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGF 349
            ||:|||..||.||.:|:|:||.|....::|.|||||:   |.:..|..|||:|||||..||.:|:
  Rat   248 VAVDASFNSFGFYKKGLYDEPNCSNNTVNHSVLVVGYGFEGNETDGNSYWLIKNSWGRKWGLRGY 312

  Fly   350 IKMLRNKENQCGIASASSYPLV 371
            :|:.:::.|.|.|||.:.||.|
  Rat   313 MKIPKDQNNFCAIASYAHYPTV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	21/58 (36%)
		Peptidase_C1	154..370	CDD:425470	106/218 (49%)
Ctsr	NP_783171.2	Inhibitor_I29	29..87	CDD:214853	21/58 (36%)
		Peptidase_C1A	116..332	CDD:239068	104/216 (48%)