Protein Alignment CtsL1 and Cts8l1

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_225128.9
• Gene: Cts8l1 / 290972
• RGDID: 1309469
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 149/345 - (43%)
• Similarity: 205/345 - (59%)
• Gaps: 16/345 - (4%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHN 94
            |...|||.:|. ||||:....:|..:: ||..:|:::.|||..| ||..|..::.||...:.:||
  Rat     1 MSPFVLLTILC-LAVARDTQSSDPSLDSEWQEWKIKYDKNYSLE-EEGQRRAVWEENMKVVKQHN 63

  Fly    95 QRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVD 159
            ..:.:||.:|.:.||.:.|:...|||::|........::.:.......|.         |||.||
  Rat    64 IEYDQGKNNFTMKVNAFGDMTGEEFRKMMIDIPVLRFRKKKXIQSHTGGY---------LPKFVD 119

  Fly   160 WRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMD 224
            ||.:|.||:||:||.|.||||||..||:|||.|||:|.|||||.|||||||...||.||..|...
  Rat   120 WRRRGYVTSVKNQGRCNSCWAFSVAGAIEGQMFRKTGRLVSLSAQNLVDCSRPEGNRGCISGHTF 184

  Fly   225 NAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVA 289
            ..|:|:.:|||::.|.:||||..:..|.:......|..:||:.|...:|..| .||||:||:||.
  Rat   185 YTFKYVWNNGGLEAESTYPYEGREGHCRYLPERSAARIKGFSIISSTEEALM-NAVATIGPISVG 248

  Fly   290 IDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIK 351
            ||||||||.|||.|:|.||:|..:.::|.||:||:   |.:..|..|||:|||.|..||..|::|
  Rat   249 IDASHESFTFYSGGIYYEPKCRNKTVNHAVLLVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMK 313

  Fly   352 MLRNKENQCGIASASSYPLV 371
            :.|.....||||:.:.||.|
  Rat   314 LARGWNKHCGIATCAFYPRV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	19/58 (33%)
		Peptidase_C1	154..370	CDD:425470	112/218 (51%)
Cts8l1	XP_225128.9	Inhibitor_I29	29..88	CDD:462410	19/59 (32%)
		Peptidase_C1A	115..331	CDD:239068	110/216 (51%)