Protein Alignment CtsL1 and Cts7

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001099569.1
• Gene: Cts7 / 290970
• RGDID: 1309226
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 136/349 - (38%)
• Similarity: 199/349 - (57%)
• Gaps: 26/349 - (7%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHN 94
            |..||.|.:|.|.| |.|....|..:: ||..:|..:.|.|..| ||:.|..::.||...|..|.
  Rat     1 MTVAVFLAILCLRA-ALAAPRPDYSLDAEWEEWKRNNAKTYSPE-EEKQRRAVWEENVKMIKWHT 63

  Fly    95 QRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTL----HKQLRAADESFKGVTFISPAHVTLP 155
            .:......:|.:.:|::.|:...|.|.:.:....||    |.|.|               :|.:|
  Rat    64 MQNGLWMNNFTIEMNEFGDMTGEEMRMMTDSSALTLRNGKHIQKR---------------NVKIP 113

  Fly   156 KSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNG 220
            |::|||..|.|..|:.||.||:|||||...::|.|.|:|:|.|:.||.|||:||:..||||.|:|
  Rat   114 KTLDWRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLIPLSVQNLIDCTVTYGNNDCSG 178

  Fly   221 GLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGP 285
            |....||:|:|:|||::.|.:|||||....|.:...........|..:|:.:|..| :|:.|.||
  Rat   179 GKPYTAFQYVKNNGGLEAEATYPYEAKLRHCRYRPERSVVKIARFFVVPRNEEALM-QALVTYGP 242

  Fly   286 VSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDK 347
            ::||||.||.||:.|..|:|:||:|....||||:|:||:   |.:.....|||:|||.|..||::
  Rat   243 IAVAIDGSHASFKRYRGGIYHEPKCRRDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGER 307

  Fly   348 GFIKMLRNKENQCGIASASSYPLV 371
            |::|:.|::.|.|||||.:.|||:
  Rat   308 GYMKLPRDQNNYCGIASYAMYPLL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	15/58 (26%)
		Peptidase_C1	154..370	CDD:425470	100/218 (46%)
Cts7	NP_001099569.1	Inhibitor_I29	29..87	CDD:214853	15/58 (26%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q91ZF2	33..50		7/17 (41%)
		Peptidase_C1A	113..329	CDD:239068	99/216 (46%)