Protein Alignment CtsL1 and Ctsl

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_037288.1
• Gene: Ctsl / 25697
• RGDID: 2448
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 341
• Identity: 176/341 - (51%)
• Similarity: 232/341 - (68%)
• Gaps: 17/341 - (4%)

  Fly    37 LPLLALLAVAQAVS---FADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFA 98
            |.|||:|.:..|::   |......:||.:|..||:.| ...||.:|..::.:|...|..||..::
  Rat     4 LLLLAVLCLGTALATPKFDQTFNAQWHQWKSTHRRLY-GTNEEEWRRAVWEKNMRMIQLHNGEYS 67

  Fly    99 EGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTK 163
            .||..|.:.:|.:.|:.:.||||::||:.:..||         ||..|..|..:.:||:||||.|
  Rat    68 NGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHK---------KGRLFQEPLMLQIPKTVDWREK 123

  Fly   164 GAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFR 228
            |.||.||:||.||||||||::|.||||.|.|:|.|:|||||||||||...||.||||||||.||:
  Rat   124 GCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQ 188

  Fly   229 YIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDAS 293
            |||:|||:|:|:||||||.|.||.:......|.|.||.|||| .||.:.:.||||||:|||:|||
  Rat   189 YIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMKPVATVGPISVAMDAS 252

  Fly   294 HESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKMLRN 355
            |.|.||||.|:|.||.|.:::|||||||||:   |||.:.:.|||||||||..||..|:||:.::
  Rat   253 HPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKD 317

  Fly   356 KENQCGIASASSYPLV 371
            :.|.||:|:|:|||:|
  Rat   318 RNNHCGLATAASYPIV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
		Peptidase_C1	154..370	CDD:425470	137/218 (63%)
Ctsl	NP_037288.1	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
		Peptidase_C1	114..332	CDD:425470	137/218 (63%)