Protein Alignment CtsL1 and Ctsh

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_037071.1
• Gene: Ctsh / 25425
• RGDID: 2447
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 134/349 - (38%)
• Similarity: 192/349 - (55%)
• Gaps: 28/349 - (8%)

  Fly    31 MRTAVLLPLLA----LLAVAQAVSFADVVMEEWH--TFKLEHRKNYQDETEERFRLKIFNENKHK 89
            |.||  ||||.    ||:...........:|::|  ::..:|:|.|... |...||::|..|..|
  Rat     1 MWTA--LPLLCAGAWLLSAGATAELTVNAIEKFHFTSWMKQHQKTYSSR-EYSHRLQVFANNWRK 62

  Fly    90 IAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTL 154
            |..||||    ..:||:.:|:::|:   .|.::.:.:.::..:...|...::...|  .|    .
  Rat    63 IQAHNQR----NHTFKMGLNQFSDM---SFAEIKHKYLWSEPQNCSATKSNYLRGT--GP----Y 114

  Fly   155 PKSVDWRTKG-AVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGC 218
            |.|:|||.|| .|:.||:||.|||||.||:|||||......||.:::|:||.||||:..:.|:||
  Rat   115 PSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGC 179

  Fly   219 NGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATV 283
            .|||...||.||..|.||..|.||||...:..|.||.....|..:...:|...||..|.||||..
  Rat   180 QGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALY 244

  Fly   284 GPVSVAIDASHESFQFYSEGVYNEPQC--DAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGD 346
            .|||.|.:.: |.|..|..|||:...|  ....::|.||.||:| :::|..||:||||||:.||:
  Rat   245 NPVSFAFEVT-EDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYG-EQNGLLYWIVKNSWGSNWGN 307

  Fly   347 KGFIKMLRNKENQCGIASASSYPL 370
            .|:..:.|.| |.||:|:.:|||:
  Rat   308 NGYFLIERGK-NMCGLAACASYPI 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	19/60 (32%)
		Peptidase_C1	154..370	CDD:425470	100/218 (46%)
Ctsh	NP_037071.1	Inhibitor_I29	33..88	CDD:462410	19/62 (31%)
		Peptidase_C1A	115..329	CDD:239068	99/216 (46%)