DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cp1 and Y71H2AR.2

DIOPT Version :9

Sequence 1:	NP_523735.2	Gene:	Cp1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001367938.1	Gene:	Y71H2AR.2 / 190615	WormBaseID:	WBGene00022189	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	77/232 - (33%)
Similarity:	121/232 - (52%)	Gaps:	30/232 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 SPAHV--TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFR-KSGVLVSLSEQNLVDC 209
            :|.|:  |..:.:|||.||.|..|||||.|.:..||:.|.::|..:.: .:|.|:|.|||.|:||
Worm    74 TPIHMDRTTEEFLDWREKGIVGPVKDQGKCNASHAFAITSSIESMYAKATNGTLLSFSEQQLIDC 138

  Fly   210 STKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-EAIDDSC---------HFNKGTVGATDRG 264
            :.: |..||......||..|:..: ||:||..||| :..::.|         |..||.|.
Worm   139 NDQ-GYKGCEEQFAMNAIGYLATH-GIETEADYPYVDKTNEKCTFDSTKSKIHLKKGVVA----- 196

  Fly   265 FTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNE--PQCDAQNLDHGVLVVGFGTD 327
                 :|:|......|...||....:.|. .|...|..|:||.  .:|.:.:....:::||:|.
Worm   197 -----EGNEVLGKVYVTNYGPAFFTMRAP-PSLYDYKIGIYNPSIEECTSTHEIRSMVIVGYGI- 254

  Fly   328 ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIAS 364
            |..:.||:||.|:||:||::|::|:.|: .|.|.:|:
Worm   255 EGEQKYWIVKGSFGTSWGEQGYMKLARD-VNACAMAT 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853
Cp1	NP_523735.2	Peptidase_C1	154..370	CDD:278538	74/224 (33%)
Y71H2AR.2	NP_001367938.1	Peptidase_C1A	84..290	CDD:239068	73/220 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910