Protein Alignment CtsL1 and cpr-2

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_507186.3
• Gene: cpr-2 / 185355
• WormBaseID: WBGene00000782
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 274
• Identity: 73/274 - (26%)
• Similarity: 116/274 - (42%)
• Gaps: 41/274 - (14%)

  Fly   120 RQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTK----GAVTAVKDQGHCGSCWA 180
            |.:...||.....:.||.:..     |:..|   .|.:.|.||:    .::..:::|.:||||||
 Worm    57 RSMHEKFNAPFPDEFRATERE-----FVLDA---TPLNFDARTRWPQCKSMKLIREQSNCGSCWA 113

  Fly   181 FSSTGALEGQHFRKSGVLVS--LSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTE---- 239
            ||:...:..:....|.....  :|..:|:.|.......||:||....||::....|.:...
 Worm   114 FSTAEVISDRTCIASNGTQQPIISPTDLLTCCGMSCGEGCDGGFPYRAFQWWARRGVVTGGDYLG 178

  Fly   240 ---KSYPYEAIDD-------------SCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATV---GP 285
               |.||....:.             ||.....|....|:.:.:......:.:|...|.:   ||
 Worm   179 TGCKPYPIRPCNSDNCVNLQTPPCRLSCQPGYRTTYTNDKNYGNSAYPVPRTVAAIQADIYYNGP 243

  Fly   286 VSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFI 350
            | ||....:|.|:.|..|:|......::. .|.|.::|:|| |.|..|||..||||:.||:.|..
 Worm   244 V-VAAFIVYEDFEKYKSGIYRHIAGRSKG-GHAVKLIGWGT-ERGTPYWLAVNSWGSQWGESGTF 305

  Fly   351 KMLRNKENQCGIAS 364
            ::||..: :|||.|
 Worm   306 RILRGVD-ECGIES 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853
		Peptidase_C1	154..370	CDD:425470	66/240 (28%)
cpr-2	NP_507186.3	Peptidase_C1A_CathepsinB	84..323	CDD:239111	66/239 (28%)