Protein Alignment Cp1 and CTSW

DIOPT Version :9

• Sequence 1: NP_523735.2
• Gene: Cp1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 111/384 - (28%)
• Similarity: 185/384 - (48%)
• Gaps: 69/384 - (17%)

  Fly    29 ITMRTAVLLPLLALLAVAQAV----SFADV------VMEEWHTFKLEHRKNYQDETEERFRLKIF 83
            :|...:.||.|| :..:||.:    ...|:      :.|.:..|:::..::|....|...||.||
Human     3 LTAHPSCLLALL-VAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIF 66

  Fly    84 NENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNY--------TLHKQLRAADES 140
               .|.:|:..:...|...:.:..|..::||...||.||   :.|        ::.:::|:.:
Human    67 ---AHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQL---YGYRRAAGGVPSMGREIRSEE-- 123

  Fly   141 FKGVTFISPAHVTLPKSVDWR-TKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQ 204
                     ...::|.|.||| ...|::.:|||.:|..|||.::.|.:|..........|.:|.|
Human   124 ---------PEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQ 179

  Fly   205 NLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYE--AIDDSCHFNKGTVGATDRGFTD 267
            .|:||. :.| :||:||.:.:||..:.:|.|:.:||.||::  .....||..|....|..:.|..
Human   180 ELLDCG-RCG-DGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIM 242

  Fly   268 IPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVY--NEPQCDAQNLDHGVLVVGFGTDESG 330
            : |.:|.::|:.:||.||::|.|:.  :..|.|.:||.  ....||.|.:||.||:||||:.:|.
Human   243 L-QNNEHRIAQYLATYGPITVTINM--KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSE 304

  Fly   331 E-------------------DYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPL 370
            |                   .||::|||||..||:||:.::.|. .|.|||   :.:||
Human   305 EGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG-SNTCGI---TKFPL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	13/58 (22%)
		Peptidase_C1	154..370	CDD:278538	81/239 (34%)
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	13/58 (22%)
		Peptidase_C1A	129..358	CDD:239068	81/237 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810