Protein Alignment Cp1 and CTSV

DIOPT Version :9

• Sequence 1: NP_523735.2
• Gene: Cp1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_001188504.1
• Gene: CTSV / 1515
• HGNCID: 2538
• Length: 334
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 171/333 - (51%)
• Similarity: 225/333 - (67%)
• Gaps: 14/333 - (4%)

  Fly    43 LAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKL 106
            |.:|.||...|..:: :|:.:|..||:.| ...||.:|..::.:|...|..||..:::||..|.:
Human    12 LGIASAVPKFDQNLDTKWYQWKATHRRLY-GANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTM 75

  Fly   107 AVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKD 171
            |:|.:.|:.:.||||:|..|.   :::.|      ||..|..|..:.||||||||.||.||.||:
Human    76 AMNAFGDMTNEEFRQMMGCFR---NQKFR------KGKVFREPLFLDLPKSVDWRKKGYVTPVKN 131

  Fly   172 QGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGI 236
            |..||||||||:|||||||.|||:|.|||||||||||||...||.|||||.|..||:|:|:|||:
Human   132 QKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGL 196

  Fly   237 DTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYS 301
            |:|:||||.|:|:.|.:......|.|.|||.:..|.||.:.:|||||||:|||:||.|.|||||.
Human   197 DSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYK 261

  Fly   302 EGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIA 363
            .|:|.||.|.::||||||||||:   |.:.:...|||||||||..||..|::|:.::|.|.||||
Human   262 SGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIA 326

  Fly   364 SASSYPLV 371
            :|:|||.|
Human   327 TAASYPNV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
		Peptidase_C1	154..370	CDD:278538	135/218 (62%)
CTSV	NP_001188504.1	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
		Peptidase_C1	114..332	CDD:306594	134/217 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	305	1.000	Domainoid score	I1367
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76699
Inparanoid	1	1.050	360	1.000	Inparanoid score	I2210
Isobase	1	0.950	-	0	Normalized mean entropy	S2922
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0000114
OrthoInspector	1	1.000	-	-		otm40851
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3411
SonicParanoid	1	1.000	-	-		X64
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.960