Protein Alignment CtsL1 and Ctsw

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_034115.2
• Gene: Ctsw / 13041
• MGIID: 1338045
• Length: 371
• Species: Mus musculus
• Alignment Length: 377
• Identity: 108/377 - (28%)
• Similarity: 172/377 - (45%)
• Gaps: 67/377 - (17%)

  Fly    33 TAVLLPLLALLAVAQAVSFADVVM------------EEWHTFKLEHRKNYQDETEERFRLKIFNE 85
            ||.|...|.||...|.:|  |.::            |.:..|::...::|.:..|...||.||
Mouse     4 TAHLSYFLVLLLAGQGLS--DSLLTKDAGPRPLELKEVFKLFQIRFNRSYWNPAEYTRRLSIF-- 64

  Fly    86 NKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGF-------NYTLHKQLRAADESFKG 143
             .|.:|:..:...|...:.:.....::||...||.||....       |.|...:.....||
Mouse    65 -AHNLAQAQRLQQEDLGTAEFGETPFSDLTEEEFGQLYGQERSPERTPNMTKKVESNTWGES--- 125

  Fly   144 VTFISPAHVTLPKSVDWR-TKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLV 207
                      :|::.||| .|..:::||:||.|..|||.::...::.....|....|.:|.|.|:
Mouse   126 ----------VPRTCDWRKAKNIISSVKNQGSCKCCWAMAAADNIQALWRIKHQQFVDVSVQELL 180

  Fly   208 DCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEA--IDDSCHFNKGTVGATDRGFTDIPQ 270
            ||. :.| ||||||.:.:|:..:.:|.|:.:||.||::.  ....|...|....|..:.||.: .
Mouse   181 DCE-RCG-NGCNGGFVWDAYLTVLNNSGLASEKDYPFQGDRKPHRCLAKKYKKVAWIQDFTML-S 242

  Fly   271 GDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVY--NEPQCDAQNLDHGVLVVGFGTDESG--- 330
            .:|:.:|..:|..||::|.|:.  :..|.|.:||.  ....||.:.:||.||:||||.::.|
Mouse   243 NNEQAIAHYLAVHGPITVTINM--KLLQHYQKGVIKATPSSCDPRQVDHSVLLVGFGKEKEGMQT 305

  Fly   331 -------------EDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 369
                         ..||::|||||..||:||:.::.|. .|.||:   :.||
Mouse   306 GTVLSHSRKRRHSSPYWILKNSWGAHWGEKGYFRLYRG-NNTCGV---TKYP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	12/58 (21%)
		Peptidase_C1	154..370	CDD:425470	78/237 (33%)
Ctsw	NP_034115.2	Inhibitor_I29	40..96	CDD:214853	12/58 (21%)
		Peptidase_C1A	127..356	CDD:239068	78/236 (33%)