Protein Alignment CtsL1 and Ctsh

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_031827.2
• Gene: Ctsh / 13036
• MGIID: 107285
• Length: 333
• Species: Mus musculus
• Alignment Length: 343
• Identity: 136/343 - (39%)
• Similarity: 191/343 - (55%)
• Gaps: 26/343 - (7%)

  Fly    37 LPLLA----LLAVAQAVSFADVVMEEWH--TFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQ 95
            ||||.    ||:...........:|::|  ::..:|:|.| ...|...||::|..|..||..|||
Mouse     5 LPLLCAGAWLLSTGATAELTVNAIEKFHFKSWMKQHQKTY-SSVEYNHRLQMFANNWRKIQAHNQ 68

  Fly    96 RFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDW 160
            |    ..:||:|:|:::|:   .|.::.:.|.::..:...|...::...|  .|    .|.|:||
Mouse    69 R----NHTFKMALNQFSDM---SFAEIKHKFLWSEPQNCSATKSNYLRGT--GP----YPSSMDW 120

  Fly   161 RTKG-AVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMD 224
            |.|| .|:.||:||.|||||.||:|||||......||.::||:||.||||:..:.|:||.|||..
Mouse   121 RKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMLSLAEQQLVDCAQAFNNHGCKGGLPS 185

  Fly   225 NAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVA 289
            .||.||..|.||..|.||||...|.||.||.....|..:...:|...||..|.||||...|||.|
Mouse   186 QAFEYILYNKGIMEEDSYPYIGKDSSCRFNPQKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFA 250

  Fly   290 IDASHESFQFYSEGVYNEPQC--DAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKM 352
            .:.: |.|..|..|||:...|  ....::|.||.||:| :::|..||:||||||:.||:.|:..:
Mouse   251 FEVT-EDFLMYKSGVYSSKSCHKTPDKVNHAVLAVGYG-EQNGLLYWIVKNSWGSQWGENGYFLI 313

  Fly   353 LRNKENQCGIASASSYPL 370
            .|.| |.||:|:.:|||:
Mouse   314 ERGK-NMCGLAACASYPI 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	20/60 (33%)
		Peptidase_C1	154..370	CDD:425470	103/218 (47%)
Ctsh	NP_031827.2	Inhibitor_I29	33..88	CDD:462410	20/62 (32%)
		Peptidase_C1A	115..329	CDD:239068	102/216 (47%)