Protein Alignment CtsL1 and LOC1274680

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_313836.5
• Gene: LOC1274680 / 1274680
• VectorBaseID: AGAMI1_008026
• Length: 334
• Species: Anopheles gambiae
• Alignment Length: 383
• Identity: 101/383 - (26%)
• Similarity: 159/383 - (41%)
• Gaps: 91/383 - (23%)

  Fly    31 MRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQ 95
            ||..||:.|..:||.. .||..|              ::.||...:.|..::....:
Mosquito     1 MRLQVLILLTVVLANG-LVSSVD--------------RHGQDPFNDDFLRRVLARAR-------- 42

  Fly    96 RFAEGKVSFKLAVNKYADLLHHEFRQL------MNGFNYTLHKQLRAADESFKGVTFISPAHVTL 154
                   ::|...|..:::..|.||.|      ..||...:.:.....|             |.:
Mosquito    43 -------TWKPDTNFQSNVHFHAFRSLKGIGESRTGFKVPIRRYEYVYD-------------VDI 87

  Fly   155 PKSVD----WRTKGAVTAVKDQGHCGSCWAFSSTGALEGQ-HFRKSGVL-VSLSEQNLVDCSTKY 213
            |:|.|    |....::.|:::||.||||||.::...:..: ....:|.: |:|:.::|:.|....
Mosquito    88 PESFDARNHWPNCESLRAIRNQGTCGSCWAVAAASVMSDRVCIHSNGTINVALAAEDLMGCCVDC 152

  Fly   214 GNNGCNGGLMD-NAFRYIKDNG--------GIDTEKSYPYEAID---DSCHFN---KGT---VGA 260
            | ||||||.:| .:|:|..|.|        ..|..|.||::..:   :.||..   |.|   ...
Mosquito   153 G-NGCNGGFLDGTSFQYWVDAGLVSGGAYNSTDGCKPYPFKPCEYPFNDCHVEISPKCTHHCRDG 216

  Fly   261 TDRGFT----------DIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNL 315
            .||.::          .:|: ||:.:...:.|.|||....|. :|....|..|||.....: |..
Mosquito   217 VDRHYSKDKLFGKVAYSVPR-DERAIRYEIMTNGPVEAGFDV-YEDVLLYKSGVYRHVYGE-QIG 278

  Fly   316 DHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIAS--ASSYPLV 371
            .|.|.::|:|.| .|..|||:.||:|..|||.|:.|.:|. .|..||.|  .:..||:
Mosquito   279 KHAVRIIGWGRD-GGIPYWLIANSYGDDWGDHGYFKFVRG-SNHLGIESKIITGLPLI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	5/58 (9%)
		Peptidase_C1	154..370	CDD:425470	76/251 (30%)
LOC1274680	XP_313836.5	Peptidase_C1A_CathepsinB	88..330	CDD:239111	76/247 (31%)