Protein Alignment CtsL1 and asic5

DIOPT Version :10

• Sequence 1: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 264
• Identity: 93/264 - (35%)
• Similarity: 140/264 - (53%)
• Gaps: 31/264 - (11%)

  Fly   108 VNKYADLLHHEF-----RQLMNGFNYTLHKQLR-AADESFKGVTFISPAHVTLPKSVDWRTKGAV 166
            :|:::||...||     |....| |||.:|..: :|.:.|            ||...|||.|..|
 Frog   118 INQFSDLSAEEFFYTYLRSFPTG-NYTSNKPFKNSAQQYF------------LPLRFDWRDKKLV 169

  Fly   167 TAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYI- 230
            |.||:|..||:|||||..||:|..:..|...|..||.|.::|||  |.::|||||..:.|.:::
 Frog   170 TPVKNQLSCGACWAFSVVGAVESAYAIKWHTLEELSVQQVIDCS--YLDSGCNGGSTNGALKWLY 232

  Fly   231 KDNGGIDTEKSYPYEAIDDSCH-FNKGTVGATDRGF-TDIPQGDEKKMAEAVATVGPVSVAIDAS 293
            :....:.....|.::|....|| |.|...|.:..|: |....|.|..|.:.:..:||:.|.::|
 Frog   233 QTKTKLVRASEYNFKAKTGLCHYFPKTDFGVSINGYETQDFSGTEDAMMKMLVDLGPMVVIVNA- 296

  Fly   294 HESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGE-DYWLVKNSWGTTWGDKGFIKMLRNKE 357
             .|:|.|..|:. :..|.:...:|.|||:|:  |::|: .||:|||||||.||..|:: .::..|
 Frog   297 -VSWQDYLGGII-QHHCSSGAPNHAVLVIGY--DKTGDTPYWIVKNSWGTAWGADGYV-YIKMGE 356

  Fly   358 NQCG 361
            |.||
 Frog   357 NICG 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	3/9 (33%)
		Peptidase_C1	154..370	CDD:425470	80/212 (38%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410	3/10 (30%)
		Peptidase_C1A	158..360	CDD:239068	77/209 (37%)
		ASC	387..816	CDD:459966